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Articles Published Processes
6/13/2025 1:39:50 PM | Browse: 3 | Download: 15
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Received |
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2025-02-13 06:49 |
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Peer-Review Started |
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2025-02-13 06:49 |
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To Make the First Decision |
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Return for Revision |
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2025-03-12 11:09 |
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Revised |
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2025-04-04 14:02 |
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Second Decision |
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2025-05-20 02:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-20 07:03 |
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Articles in Press |
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2025-05-20 07:03 |
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Publication Fee Transferred |
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2025-04-14 00:59 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-30 02:47 |
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Publish the Manuscript Online |
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2025-06-13 13:39 |
| ISSN |
1948-5204 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jin-Rui Wei, Yi-Na Ouyang, Meng-Ting Tang, Jia-Zhen Yuan, Pei-Li Wang, Li-He Jiang and Li-Chuan Wu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
82260715 |
| the Middle-Aged and Young Teachers in Colleges and Universities in Guangxi Basic Ability Promotion Project |
2024KY0302 |
| Guangxi Collaborative Innovation Center for Research on Functional Ingredients of Agricultur-al Residues |
CICAR2016-P6 |
| the Grant of research project on high-level talents of Youjiang Medical College for Nationalities |
YY2021SK002 |
| Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province |
202300011 |
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| Corresponding Author |
Li-He Jiang, PhD, Professor, School of Basic Medical Sciences, Youjiang Medical University for Nationalities, No. 98 Chengxiang Road, Baise 533000, Guangxi Zhuang Autonomous Region, China. jianglihe@ymun.edu.cn |
| Key Words |
Colorectal cancer; Weighted gene co-expression network analysis; Charged multivesicular body protein 7; Metastasis biomarker; Prognosis |
| Core Tip |
Tumor metastasis is the main reason leading to death in colorectal cancer (CRC). Unveiling CRC metastasis related biomarkers is of great significance. In this study, charged multivesicular body protein 7 (CHMP7) was identified as a prognostic factor correlated with metastasis in CRC. CHMP7 showed a lower expression in CRC patients with metastasis and CRC cell lines with high metastasis potential. The expression of CHMP7 was significantly correlated with normal, metastatic tumor, pathologic stage, and lymphatic invasion (P < 0.05). CRC patients with higher expression of CHMP7 exhibited better overall survival. Besides, Gene Set Enrichment Analysis results showed that CHMP7 might be involved in metastatic related pathways. |
| Publish Date |
2025-06-13 13:39 |
| Citation |
<p>Wei JR, Ouyang YN, Tang MT, Yuan JZ, Wang PL, Jiang LH, Wu LC. Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer. <i>World J Gastrointest Oncol</i> 2025; 17(6): 105967</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i6/105967.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i6.105967 |
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