| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Prognosis of ulcerative colitis differs between patients with complete and partial mucosal healing, which can be predicted from the platelet count
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Asuka Nakarai, Jun Kato, Sakiko Hiraoka, Toshihiro Inokuchi, Daisuke Takei, Yuki Moritou, Mitsuhiro Akita, Sakuma Takahashi, Keisuke Hori, Keita Harada, Hiroyuki Okada and Kazuhide Yamamoto |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Sakiko Hiraoka, MD, Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan. sakikoh@cc.okayama-u.ac.jp |
| Key Words |
Ulcerative colitis; Mucosal healing; Platelet count; Mayo endoscopic subscore; Platelet count |
| Core Tip |
Mucosal healing has been recognized as the treatment goal of ulcerative colitis (UC). Although many previous reports defined mucosal healing as Mayo endoscopic subscore (MES) of 0 or 1, the difference in prognosis between patients with MES 0 and those with MES 1 has scarcely been evaluated. This paper indicated that the relapse rate differed greatly between patients with MES 0 and MES 1, and that the treatment goal of UC should be MES 0. We also demonstrated that a shift from MES 0 to MES 1 in clinically stable UC patients can be predicted by monitoring platelet count. |
| Publish Date |
2015-01-06 09:08 |
| Citation |
Nakarai A, Kato J, Hiraoka S, Inokuchi T, Takei D, Moritou Y, Akita M, Takahashi S, Hori K, Harada K, Okada H, Yamamoto K. Prognosis of ulcerative colitis differs between patients with complete and partial mucosal healing, which can be predicted from the platelet count. World J Gastroenterol 2014; 20(48): 18367-18374 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i48/18367.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i48.18367 |
