Publication Name	World Journal of Psychiatry
Manuscript ID	106062
Country	Japan

Received	2025-02-17 09:33
Peer-Review Started	2025-02-17 09:33
To Make the First Decision
Return for Revision	2025-03-19 07:49
Revised	2025-03-20 05:05
Second Decision	2025-04-14 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-14 06:59
Articles in Press	2025-04-14 06:59
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-04-20 22:56
Typeset the Manuscript	2025-06-21 03:12
Publish the Manuscript Online	2025-07-10 03:52

ISSN	2220-3206 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Psychiatry
Manuscript Type	Editorial
Article Title	Gut-skin-brain axis in people suffering from sepsis with acute skin failure
Manuscript Source	Invited Manuscript
All Author List	Takahiko Nagamine
ORCID	Author(s) ORCID Number Takahiko Nagamine http://orcid.org/0000-0002-0690-6271
Funding Agency and Grant Number
Corresponding Author	Takahiko Nagamine, MD, PhD, Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp
Key Words	Acute skin failure; Anxiety; Gut-skin-brain axis; Insomnia; Sepsis
Core Tip	Acute skin failure tends to cause insomnia and anxiety. The skin, along with the gut, is an organ that functions as a barrier, forming the gut-skin-brain axis. The gut-skin-brain axis is a bidirectional relationship mediated by the immune system, hormones, and the autonomic nervous system. Studying the gut-skin-brain axis holds immense promise for understanding mental illness due to the intricate and bidirectional communication network it represents. In essence, the gut-skin-brain axis provides a framework for understanding how interactions between the gut, skin, and brain can influence mental health, opening new avenues for prevention and treatment.
Publish Date	2025-07-10 03:52
Citation	<p>Nagamine T. Gut-skin-brain axis in people suffering from sepsis with acute skin failure. <i>World J Psychiatry</i> 2025; 15(7): 106062</p>
URL	https://www.wjgnet.com/2220-3206/full/v15/i7/106062.htm
DOI	https://dx.doi.org/10.5498/wjp.v15.i7.106062

Full Article (PDF)	WJP-15-106062-with-cover.pdf
Manuscript File	106062_Auto_Edited_062037.docx
Answering Reviewers	106062-answering-reviewers.pdf
Audio Core Tip	106062-audio.mp3
Conflict-of-Interest Disclosure Form	106062-conflict-of-interest-statement.pdf
Copyright License Agreement	106062-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	106062-non-native-speakers.pdf
Peer-review Report	106062-peer-reviews.pdf
Scientific Misconduct Check	106062-scientific-misconduct-check.png
Scientific Editor Work List	106062-scientific-editor-work-list.pdf
CrossCheck Report	106062-crosscheck-report.pdf