BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/23/2025 9:07:55 AM | Browse: 8 | Download: 42
Publication Name World Journal of Cardiology
Manuscript ID 106123
Country United States
Received
2025-02-17 03:19
Peer-Review Started
2025-02-17 03:20
To Make the First Decision
Return for Revision
2025-04-02 11:18
Revised
2025-04-06 05:08
Second Decision
2025-04-28 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-28 08:15
Articles in Press
2025-04-28 08:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-05-15 06:36
Publish the Manuscript Online
2025-05-23 09:07
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Systematic Reviews
Article Title Circulating microRNAs in predicting fibrosis in hypertrophic cardiomyopathy: A systematic review
Manuscript Source Invited Manuscript
All Author List Maneeth Mylavarapu, Lakshmi Sai Meghana Kodali, Roopeessh Vempati, Jai Sivanandan Nagarajan, Ankit Vyas and Rupak Desai
ORCID
Author(s) ORCID Number
Maneeth Mylavarapu http://orcid.org/0009-0004-2367-9615
Lakshmi Sai Meghana Kodali http://orcid.org/0009-0009-2200-8234
Roopeessh Vempati http://orcid.org/0000-0001-5966-909X
Jai Sivanandan Nagarajan http://orcid.org/0000-0003-1805-064X
Ankit Vyas http://orcid.org/0000-0003-1668-4120
Rupak Desai http://orcid.org/0000-0002-5315-6426
Funding Agency and Grant Number
Corresponding Author Rupak Desai, Senior Researcher, Outcomes Research, Independent Researcher, Scottdale, Atlanta, GA 30079, United States. drrupakdesai@gmail.com
Key Words Circulating micro RNAs; Hypertrophic cardiomyopathy; Myocardial fibrosis; Cardiac magnetic resonance; Late gadolinium enhancement; Systematic Review
Core Tip Circulating microRNAs (miRNA) show promise as non-invasive biomarkers for myocardial fibrosis in hypertrophic cardiomyopathy (HCM). Our systematic review of eight studies identified miRNAs miR-21, miR-29a, and miR-221 as frequently dysregulated, with elevated miR-21 and miR-29a correlating with increased fibrosis detected by cardiac magnetic resonance imaging. These findings suggest that miRNAs could be a less invasive approach to the detection of fibrosis in HCM. However, the clinical validation of these findings has to be further validated with further research.
Publish Date 2025-05-23 09:07
Citation <p>Mylavarapu M, Kodali LSM, Vempati R, Nagarajan JS, Vyas A, Desai R. Circulating microRNAs in predicting fibrosis in hypertrophic cardiomyopathy: A systematic review. <i>World J Cardiol</i> 2025; 17(5): 106123</p>
URL https://www.wjgnet.com/1949-8462/full/v17/i5/106123.htm
DOI https://dx.doi.org/10.4330/wjc.v17.i5.106123
Full Article (PDF) WJC-17-106123-with-cover.pdf
PRISMA 2009 Checklist 106123-PRISMA-2009-Checklist.pdf
Manuscript File 106123_Auto_Edited_055057.docx
Answering Reviewers 106123-answering-reviewers.pdf
Audio Core Tip 106123-audio.m4a
Biostatistics Review Certificate 106123-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 106123-conflict-of-interest-statement.pdf
Copyright License Agreement 106123-copyright-assignment.pdf
Supplementary Material 106123-supplementary-material.pdf
Peer-review Report 106123-peer-reviews.pdf
Scientific Editor Work List 106123-scientific-editor-work-list.pdf
CrossCheck Report 106123-crosscheck-report.pdf