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Articles Published Processes
5/23/2025 9:07:55 AM | Browse: 223 | Download: 580
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Received |
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2025-02-17 03:19 |
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Peer-Review Started |
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2025-02-17 03:20 |
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First Decision by Editorial Office Director |
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2025-04-02 11:18 |
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Return for Revision |
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2025-04-02 11:18 |
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Revised |
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2025-04-06 05:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-04-28 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-04-28 08:15 |
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Articles in Press |
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2025-04-28 08:15 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-15 06:36 |
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Publish the Manuscript Online |
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2025-05-23 09:07 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Circulating microRNAs in predicting fibrosis in hypertrophic cardiomyopathy: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maneeth Mylavarapu, Lakshmi Sai Meghana Kodali, Roopeessh Vempati, Jai Sivanandan Nagarajan, Ankit Vyas and Rupak Desai |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Rupak Desai, Senior Researcher, Outcomes Research, Independent Researcher, Scottdale, Atlanta, GA 30079, United States. drrupakdesai@gmail.com |
| Key Words |
Circulating micro RNAs; Hypertrophic cardiomyopathy; Myocardial fibrosis; Cardiac magnetic resonance; Late gadolinium enhancement; Systematic Review |
| Core Tip |
Circulating microRNAs (miRNA) show promise as non-invasive biomarkers for myocardial fibrosis in hypertrophic cardiomyopathy (HCM). Our systematic review of eight studies identified miRNAs miR-21, miR-29a, and miR-221 as frequently dysregulated, with elevated miR-21 and miR-29a correlating with increased fibrosis detected by cardiac magnetic resonance imaging. These findings suggest that miRNAs could be a less invasive approach to the detection of fibrosis in HCM. However, the clinical validation of these findings has to be further validated with further research. |
| Publish Date |
2025-05-23 09:07 |
| Citation |
Mylavarapu M, Kodali LSM, Vempati R, Nagarajan JS, Vyas A, Desai R. Circulating microRNAs in predicting fibrosis in hypertrophic cardiomyopathy: A systematic review. World J Cardiol 2025; 17(5): 106123 |
| URL |
https://www.wjgnet.com/1949-8462/full/v17/i5/106123.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v17.i5.106123 |
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