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Articles Published Processes
5/27/2025 7:04:47 AM | Browse: 4 | Download: 21
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Received |
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2025-02-17 09:42 |
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Peer-Review Started |
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2025-02-27 00:54 |
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To Make the First Decision |
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Return for Revision |
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2025-03-20 09:07 |
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Revised |
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2025-03-28 08:12 |
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Second Decision |
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2025-04-24 02:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-24 09:11 |
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Articles in Press |
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2025-04-24 09:11 |
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Publication Fee Transferred |
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2025-03-31 04:47 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-14 08:23 |
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Publish the Manuscript Online |
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2025-05-27 07:04 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Microbial characteristics of gut microbiome dysbiosis in patients with chronic liver disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chi Ma, Juan Yang, Xin-Nian Fu, Jiang-Yan Luo, Pei Liu, Xue-Li Zeng, Xin-Yi Li, Shun-Ling Zhang and Sheng Zheng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Yunnan Provincial High-Level Science and Technology Talent and Innovation Team Selection Special - Young Academic and Technical Leader Backup Talent Project |
No. 202405AC350067 |
| Yunnan Provincial Department of Education Scientific Research Fund Project |
No. 2024Y919 and No. 2024Y920 |
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| Corresponding Author |
Sheng Zheng, Associate Professor, Department of Gastroenterology, The Third People’s Hospital of Yunnan Province, No. 292 Beijing Road, Guandu District, Kunming 650011, Yunnan Province, China. zheng_sheng523@163.com |
| Key Words |
Gut microbiota; 16SrDNA; Chronic hepatitis B; Liver cirrhosis; Hepatocellular carcinoma; Dysbiosis |
| Core Tip |
The study emphasized the microbial characteristics of gut microbiome dysbiosis at different stages of chronic liver disease (CLD). In this study, 16SrDNA sequencing was used to detect the gut microbiome characteristics in the CLD population. The reduced abundance of short-chain fatty acid-producing bacteria in the intestine, alongside the increased abundance of gram-negative bacteria such as Escherichia_Shigella and Parabacteroides, may promote the progression of CLD by compromising the integrity of the intestinal mucosal barrier. The results of this study may provide new insights for developing novel diagnostic and therapeutic strategies for CLD. |
| Publish Date |
2025-05-27 07:04 |
| Citation |
<p>Ma C, Yang J, Fu XN, Luo JY, Liu P, Zeng XL, Li XY, Zhang SL, Zheng S. Microbial characteristics of gut microbiome dysbiosis in patients with chronic liver disease. <i>World J Hepatol</i> 2025; 17(5): 106124</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i5/106124.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i5.106124 |
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