BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/16/2025 7:21:11 AM | Browse: 18 | Download: 48
Publication Name World Journal of Orthopedics
Manuscript ID 106145
Country United States
Received
2025-02-19 09:55
Peer-Review Started
2025-02-19 09:55
To Make the First Decision
Return for Revision
2025-03-21 07:06
Revised
2025-03-25 22:54
Second Decision
2025-04-17 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-17 09:08
Articles in Press
2025-04-17 09:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-05-05 10:12
Publish the Manuscript Online
2025-05-16 07:21
ISSN 2218-5836 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Meta-Analysis
Article Title Role of neutrophil to lymphocyte ratio in osteoarthritis: A systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Maryam Salimi, Shokoufeh Khanzadeh, Brandon Lucke-Wold, Arshin Ghaedi and Austin V Stone
ORCID
Author(s) ORCID Number
Maryam Salimi http://orcid.org/0000-0001-9771-7048
Shokoufeh Khanzadeh http://orcid.org/0000-0002-4177-8746
Brandon Lucke-Wold http://orcid.org/0000-0001-6577-4080
Arshin Ghaedi http://orcid.org/0000-0001-9584-0026
Austin V Stone http://orcid.org/0000-0002-9406-7884
Funding Agency and Grant Number
Corresponding Author Austin V Stone, Associate Professor, MD, PhD, Department of Orthopaedic Surgery and Sports Medicine, University of Kentucky, Suite K401, 740 S Limestone, Lexington, KY 40536, United States. austin.stone@uky.edu
Key Words Neutrophil to lymphocyte ratio; Osteoarthritis; Meta-analysis; Inflammatory biomarker; Systemic inflammation
Core Tip This systematic review and meta-analysis evaluate the role of the neutrophil-to-lymphocyte ratio (NLR) in osteoarthritis (OA). Our findings indicate that OA patients have significantly higher NLR levels than healthy controls, suggesting its potential as an inflammatory biomarker. However, NLR does not significantly correlate with OA severity or study design, limiting its utility in assessing disease progression. Further research is needed to clarify NLR’s clinical relevance in OA diagnosis and management.
Publish Date 2025-05-16 07:21
Citation <p>Salimi M, Khanzadeh S, Lucke-Wold B, Ghaedi A, Stone AV. Role of neutrophil to lymphocyte ratio in osteoarthritis: A systematic review and meta-analysis. <i>World J Orthop</i> 2025; 16(5): 106145</p>
URL https://www.wjgnet.com/2218-5836/full/v16/i5/106145.htm
DOI https://dx.doi.org/10.5312/wjo.v16.i5.106145
Full Article (PDF) WJO-16-106145-with-cover.pdf
PRISMA 2009 Checklist 106145-PRISMA-2009-Checklist.pdf
Manuscript File 106145_Auto_Edited_073027.docx
Answering Reviewers 106145-answering-reviewers.pdf
Audio Core Tip 106145-audio.m4a
Biostatistics Review Certificate 106145-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 106145-conflict-of-interest-statement.pdf
Copyright License Agreement 106145-copyright-assignment.pdf
Peer-review Report 106145-peer-reviews.pdf
Scientific Misconduct Check 106145-scientific-misconduct-check.png
Scientific Editor Work List 106145-scientific-editor-work-list.pdf
CrossCheck Report 106145-crosscheck-report.pdf