| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Meta-analysis of factors associated with the incidence of comorbid depression and anxiety in patients with chronic hepatitis B
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Guo, Li-Xia He, Pei-Qi Wan, Xiu-Mei Zhen, Fang Xiao, Wen-Bin Wu, Ming-Hua Su, Bi-Hua Gao and Zhi-Hong Liu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Beihai City Science and Technology Program Projects |
Beikehe 2023158020 |
|
| Corresponding Author |
Zhi-Hong Liu, Department of Infectious Diseases, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. liuzh308@163.com |
| Key Words |
Chronic hepatitis B; Depression; Anxiety; Correlative factors; Meta-analysis |
| Core Tip |
Patients with chronic hepatitis B may experience a significant burden of mental-health issues, with 30.1% experiencing depression, 40.2% anxiety, and 33.7% overall negative emotions. Higher educational level was a protective factor (odds ratio = 0.43) by enhancing self-management and disease understanding, whereas older age, longer treatment duration, comorbidities, poor sleep quality, emotional instability, frequent hepatitis relapses, and severe hepatitis status all elevated the risk of comorbid depression and anxiety. Clinically, early identification of high-risk groups and targeted interventions, such as education-based counseling and sleep management, are crucial for improving mental-health outcomes, although current research heterogeneity from diverse assessment tools and regional sampling indicates the need for standardized broader population studies in the future. |
| Publish Date |
2025-11-04 02:41 |
| Citation |
<p>Guo L, He LX, Wan PQ, Zhen XM, Xiao F, Wu WB, Su MH, Gao BH, Liu ZH. Meta-analysis of factors associated with the incidence of comorbid depression and anxiety in patients with chronic hepatitis B. <i>World J Psychiatry</i> 2025; 15(11): 106164</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i11/106164.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i11.106164 |
