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Articles Published Processes
5/27/2025 7:04:49 AM | Browse: 5 | Download: 15
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Received |
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2025-02-18 03:50 |
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Peer-Review Started |
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2025-02-20 07:20 |
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2025-03-27 10:36 |
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2025-04-09 19:15 |
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2025-05-06 02:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-07 12:41 |
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Articles in Press |
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2025-05-07 12:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-05-14 08:08 |
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Publish the Manuscript Online |
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2025-05-27 07:04 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Sarcopenia and frailty: An in-depth analysis of the pathophysiology and effect on liver transplant candidates
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Grigorios Christodoulidis, Kyriaki Tsagkidou, Dimitra Bartzi, Ioana A Prisacariu, Eirini S Agko, Konstantinos E Koumarelas and Dimitrios Zacharoulis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Grigorios Christodoulidis, MD, PhD, Department of General Surgery, University Hospital of Larissa, Mezourlo, Larissa 41110, Thessalia, Greece. gregsurg@yahoo.gr |
| Key Words |
Sarcopenia; Liver transplant; Liver fibrosis; End-stage liver disease; Frailty; Cirrhosis; Chronic liver disease; Pathophysiology; Artificial intelligence; Muscle mass loss |
| Core Tip |
Cirrhosis is a term used to describe a complex pathophysiological condition, which causes diffuse damage to the liver. These conditions lead to overall hepatocyte degeneration and necrosis, excessive fibrosis and the development of regenerative nodules as fibrous tissue encases surviving hepatocytes. The term sarcopenia, was initially introduced by Rosenberg in 1989, initially referred only to the loss of muscle mass, but later, the quality of muscle mass was also included. Frailty is a common condition in patients with cirrhosis, and it is associated with increased morbidity and mortality. Sarcopenia and frailty are distinct features that share common pathophysiologic mechanisms, both affecting the course of action in candidates in pre- and post-liver transplantation. |
| Publish Date |
2025-05-27 07:04 |
| Citation |
<p>Christodoulidis G, Tsagkidou K, Bartzi D, Prisacariu IA, Agko ES, Koumarelas KE, Zacharoulis D. Sarcopenia and frailty: An in-depth analysis of the pathophysiology and effect on liver transplant candidates. <i>World J Hepatol</i> 2025; 17(5): 106182</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i5/106182.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i5.106182 |
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