| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in peritoneal dialysis patients: A systematic review and meta-analysis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Nanush Damarlapally, Roopeessh Vempati, Denise Mourad, Srivatsa Surya Vasudevan, Gaurav Mathur, Afrasayab Khan, Prathibha Banda, Harshavardhan Polamarasetty, Shaylika Chauhan, Nirmala Manjappachar, Talha Bhatti and Rupak Desai |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Shaylika Chauhan, Assistant Professor, FACP, MD, Department of Internal Medicine, Geisinger Health System, 1000 E Mountain Blvd, Wikes-Barre, PA 18707, United States. drshaylikachauhan@gmail.com |
| Key Words |
Neutrophil-to-lymphocyte ratio; Peritoneal dialysis; All-cause mortality; Cardiovascular mortality; End stage renal disease; Chronic renal failure; Mortality; Dialysis; Elderly; Cardiac arrest |
| Core Tip |
Inflammation plays a silent but an important role in patients undergoing peritoneal dialysis (PD). This meta-analysis reveals that a simple, and inexpensive blood marker such as elevated neutrophil-to-lymphocyte ratio (NLR) (NLR > 3) can significantly predict all-cause and cardiovascular mortality in this vulnerable group. With data from over 4300 patients, our study also identified age as a key confounder, urging clinicians to interpret NLR levels with caution in older adults. These findings position NLR as a powerful, accessible tool for early risk detection and tailored intervention in PD care. |
| Publish Date |
2026-02-10 10:35 |
| Citation |
Damarlapally N, Vempati R, Mourad D, Vasudevan SS, Mathur G, Khan A, Banda P, Polamarasetty H, Chauhan S, Manjappachar N, Bhatti T, Desai R. Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in peritoneal dialysis patients: A systematic review and meta-analysis. World J Methodol 2026; 16(1): 106277 |
| URL |
https://www.wjgnet.com/2222-0682/full/v16/i1/106277.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v16.i1.106277 |
