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9/24/2025 3:48:36 AM | Browse: 31 | Download: 196
Publication Name World Journal of Stem Cells
Manuscript ID 106381
Country China
Received
2025-03-21 17:04
Peer-Review Started
2025-03-24 02:00
First Decision by Editorial Office Director
2025-05-15 02:39
Return for Revision
2025-05-15 02:39
Revised
2025-05-16 11:11
Publication Fee Transferred
Second Decision by Editor
2025-07-28 05:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-08-04 08:48
Articles in Press
2025-08-04 08:48
Edit the Manuscript by Language Editor
2025-08-10 02:21
Typeset the Manuscript
2025-09-06 15:04
Publish the Manuscript Online
2025-09-24 03:48
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Study
Article Title Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer patients
Manuscript Source Unsolicited Manuscript
All Author List Tao Lin, Si-Cong Jiang, Xian-Ming He, Wen-Zhen Xu, Cai-Jin Jin and You-Dan Guo
ORCID
Author(s) ORCID Number
You-Dan Guo http://orcid.org/0009-0004-6984-2377
Funding Agency and Grant Number
Corresponding Author You-Dan Guo, Department of Respiratory Disease, Jiangxi Provincial People’s Hospital, No. 92 Aiguo Road, Nanchang 330006, Jiangxi Province, China. 13970945069@163.com
Key Words Stage IIIA non-small cell lung cancer; Tumor stem cell markers; Tumor stemness index; Prognosis survival; Relationship
Core Tip In patients with stage IIIA non-small cell lung cancer, older age and the presence of micropapillary components are significantly associated with worse overall survival, indicating their potential role in risk stratification. Furthermore, high expression of octamer-binding transcription factor 4 and elevated mRNA expression-based stemness index, both markers of tumor stemness, are closely linked to poor prognosis. These factors may serve not only as important prognostic indicators but also as potential therapeutic targets, contributing to more personalized and effective treatment strategies in clinical practice.
Publish Date 2025-09-24 03:48
Citation

Lin T, Jiang SC, He XM, Xu WZ, Jin CJ, Guo YD. Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer patients. World J Stem Cells 2025; 17(9): 106381

URL https://www.wjgnet.com/1948-0210/full/v17/i9/106381.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i9.106381
Full Article (PDF) WJSC-17-106381-with-cover.pdf
Manuscript File 106381_Auto_Edited_062051.docx
Answering Reviewers 106381-answering-reviewers.pdf
Audio Core Tip 106381-audio.mp3
Biostatistics Review Certificate 106381-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 106381-conflict-of-interest-statement.pdf
Copyright License Agreement 106381-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 106381-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 106381-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 106381-non-native-speakers.pdf
Peer-review Report 106381-peer-reviews.pdf
Scientific Misconduct Check 106381-scientific-misconduct-check.png
Scientific Editor Work List 106381-scientific-editor-work-list.pdf
CrossCheck Report 106381-crosscheck-report.pdf