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6/13/2025 1:39:39 PM | Browse: 16 | Download: 196
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 106393
Country China
Received
2025-03-12 08:56
Peer-Review Started
2025-03-12 08:57
To Make the First Decision
Return for Revision
2025-04-02 09:23
Revised
2025-04-03 12:33
Second Decision
2025-04-25 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-25 05:58
Articles in Press
2025-04-25 05:58
Publication Fee Transferred
2025-04-09 06:15
Edit the Manuscript by Language Editor
2025-05-01 03:46
Typeset the Manuscript
2025-06-02 13:44
Publish the Manuscript Online
2025-06-13 13:39
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly colorectal cancer patients
Manuscript Source Unsolicited Manuscript
All Author List Shuai-Bo Qiao, Ming-Liao Niu, Wei-Tao Liang, Long-Jiang Zhang, Xiang Chen and Ying-Kun Zhu
ORCID
Author(s) ORCID Number
Long-Jiang Zhang http://orcid.org/0009-0005-5880-3951
Funding Agency and Grant Number
Corresponding Author Long-Jiang Zhang, Chief Physician, Department of Anorectal Surgery, Henan Province Hospital of Traditional Chinese Medicine, No. 6 Dongfeng Road, Zhengzhou 450000, Henan Province, China. hnszyyzlj@163.com
Key Words Predictive value; Chemotherapy efficacy; Correlation; Gut microbiome dysbiosis; Soluble receptor for advanced glycation end products; Serum S100 calcium-binding protein A12; Colorectal cancer; Elderly
Core Tip Elevated serum S100 calcium-binding protein A12 and soluble receptor for advanced glycation end products in elderly colorectal cancer patients reflect gut microbiome dysbiosis and systemic inflammation, driven by interleukin-6/tumor necrosis factor-α signaling. Their post-chemotherapy decline parallels microbiota restoration, supporting a microbiome-inflammation-biomarker axis. The combined biomarker model offers robust clinical utility for chemotherapy efficacy prediction and personalized therapeutic strategies.
Publish Date 2025-06-13 13:39
Citation <p>Qiao SB, Niu ML, Liang WT, Zhang LJ, Chen X, Zhu YK. Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly colorectal cancer patients. <i>World J Gastrointest Oncol</i> 2025; 17(6): 106393</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i6/106393.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i6.106393
Full Article (PDF) WJGO-17-106393-with-cover.pdf
Manuscript File 106393_Auto_Edited_064543.docx
Answering Reviewers 106393-answering-reviewers.pdf
Audio Core Tip 106393-audio.mp3
Biostatistics Review Certificate 106393-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 106393-conflict-of-interest-statement.pdf
Copyright License Agreement 106393-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 106393-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 106393-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 106393-non-native-speakers.pdf
Supplementary Material 106393-supplementary-material.pdf
Peer-review Report 106393-peer-reviews.pdf
Scientific Misconduct Check 106393-scientific-misconduct-check.png
Scientific Editor Work List 106393-scientific-editor-work-list.pdf
CrossCheck Report 106393-crosscheck-report.pdf