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Articles Published Processes
6/13/2025 1:39:39 PM | Browse: 16 | Download: 196
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Received |
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2025-03-12 08:56 |
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Peer-Review Started |
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2025-03-12 08:57 |
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To Make the First Decision |
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Return for Revision |
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2025-04-02 09:23 |
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Revised |
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2025-04-03 12:33 |
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Second Decision |
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2025-04-25 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-25 05:58 |
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Articles in Press |
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2025-04-25 05:58 |
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Publication Fee Transferred |
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2025-04-09 06:15 |
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Edit the Manuscript by Language Editor |
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2025-05-01 03:46 |
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Typeset the Manuscript |
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2025-06-02 13:44 |
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Publish the Manuscript Online |
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2025-06-13 13:39 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Study |
Article Title |
Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly colorectal cancer patients
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Shuai-Bo Qiao, Ming-Liao Niu, Wei-Tao Liang, Long-Jiang Zhang, Xiang Chen and Ying-Kun Zhu |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Long-Jiang Zhang, Chief Physician, Department of Anorectal Surgery, Henan Province Hospital of Traditional Chinese Medicine, No. 6 Dongfeng Road, Zhengzhou 450000, Henan Province, China. hnszyyzlj@163.com |
Key Words |
Predictive value; Chemotherapy efficacy; Correlation; Gut microbiome dysbiosis; Soluble receptor for advanced glycation end products; Serum S100 calcium-binding protein A12; Colorectal cancer; Elderly |
Core Tip |
Elevated serum S100 calcium-binding protein A12 and soluble receptor for advanced glycation end products in elderly colorectal cancer patients reflect gut microbiome dysbiosis and systemic inflammation, driven by interleukin-6/tumor necrosis factor-α signaling. Their post-chemotherapy decline parallels microbiota restoration, supporting a microbiome-inflammation-biomarker axis. The combined biomarker model offers robust clinical utility for chemotherapy efficacy prediction and personalized therapeutic strategies. |
Publish Date |
2025-06-13 13:39 |
Citation |
<p>Qiao SB, Niu ML, Liang WT, Zhang LJ, Chen X, Zhu YK. Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly colorectal cancer patients. <i>World J Gastrointest Oncol</i> 2025; 17(6): 106393</p> |
URL |
https://www.wjgnet.com/1948-5204/full/v17/i6/106393.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v17.i6.106393 |
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