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Articles Published Processes
6/13/2025 1:39:39 PM | Browse: 45 | Download: 372
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Received |
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2025-03-12 08:56 |
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Peer-Review Started |
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2025-03-12 08:57 |
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First Decision by Editorial Office Director |
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2025-04-02 09:23 |
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Return for Revision |
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2025-04-02 09:23 |
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Revised |
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2025-04-03 12:33 |
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Publication Fee Transferred |
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2025-04-09 06:15 |
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Second Decision by Editor |
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2025-04-25 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-04-25 05:58 |
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Articles in Press |
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2025-04-25 05:58 |
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Edit the Manuscript by Language Editor |
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2025-05-01 03:46 |
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Typeset the Manuscript |
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2025-06-02 13:44 |
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Publish the Manuscript Online |
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2025-06-13 13:39 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly colorectal cancer patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shuai-Bo Qiao, Ming-Liao Niu, Wei-Tao Liang, Long-Jiang Zhang, Xiang Chen and Ying-Kun Zhu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Long-Jiang Zhang, Chief Physician, Department of Anorectal Surgery, Henan Province Hospital of Traditional Chinese Medicine, No. 6 Dongfeng Road, Zhengzhou 450000, Henan Province, China. hnszyyzlj@163.com |
| Key Words |
Predictive value; Chemotherapy efficacy; Correlation; Gut microbiome dysbiosis; Soluble receptor for advanced glycation end products; Serum S100 calcium-binding protein A12; Colorectal cancer; Elderly |
| Core Tip |
Elevated serum S100 calcium-binding protein A12 and soluble receptor for advanced glycation end products in elderly colorectal cancer patients reflect gut microbiome dysbiosis and systemic inflammation, driven by interleukin-6/tumor necrosis factor-α signaling. Their post-chemotherapy decline parallels microbiota restoration, supporting a microbiome-inflammation-biomarker axis. The combined biomarker model offers robust clinical utility for chemotherapy efficacy prediction and personalized therapeutic strategies. |
| Publish Date |
2025-06-13 13:39 |
| Citation |
Qiao SB, Niu ML, Liang WT, Zhang LJ, Chen X, Zhu YK. Analysis of serum S100A12, soluble advanced glycation end products receptor, and gut microbiome in elderly colorectal cancer patients. World J Gastrointest Oncol 2025; 17(6): 106393 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i6/106393.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i6.106393 |
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