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Articles Published Processes
10/24/2025 7:36:26 AM | Browse: 167 | Download: 261
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Received |
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2025-05-16 09:19 |
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Peer-Review Started |
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2025-05-16 09:20 |
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First Decision by Editorial Office Director |
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2025-06-07 05:45 |
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Return for Revision |
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2025-06-07 05:45 |
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Revised |
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2025-06-17 05:49 |
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Publication Fee Transferred |
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2025-07-07 03:43 |
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Second Decision by Editor |
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2025-08-22 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-08-22 08:25 |
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Articles in Press |
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2025-08-22 08:25 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-10-11 01:39 |
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Publish the Manuscript Online |
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2025-10-24 07:36 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Retrospective Study |
| Article Title |
Association between hepatitis B virus markers and liver fibrosis staging in patients with chronic hepatitis B
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Jing Huang, Xiao Zheng and Kai Wang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xiao-Jing Huang, Department of Infection, Hangzhou Linping District First People’s Hospital, No. 369, Yingbin Road, Nanyuan Street, Linping District, Hangzhou 311100, Zhejiang Province, China. 13306521018@163.com |
| Key Words |
Hepatitis B core antibody; Hepatitis B virus DNA; Hepatitis B surface antigen; Chronic hepatitis B; Liver fibrosis staging |
| Core Tip |
By combining three serum biomarkers, hepatitis B core antibody, hepatitis B virus-DNA, and hepatitis B surface antigen, this study proposes a cost-effective, non-invasive diagnostic approach for assessing chronic hepatitis B-related liver fibrosis (LF) staging, providing advantages in operational convenience and repeatability. The multi-parameter model demonstrated superior diagnostic performance without compromising either sensitivity or specificity. Further, a strong correlation of hepatitis B core antibody and hepatitis B virus-DNA with LF progression was determined. Altogether, a promising non-invasive serological tool for LF staging is proposed in this study, providing a cost-effective solution to improve clinical diagnostics and patient care. |
| Publish Date |
2025-10-24 07:36 |
| Citation |
Huang XJ, Zheng X, Wang K. Association between hepatitis B virus markers and liver fibrosis staging in patients with chronic hepatitis B. World J Gastrointest Surg 2025; 17(10): 106414 |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i10/106414.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i10.106414 |
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