BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/28/2025 7:32:56 AM | Browse: 6 | Download: 7
 |
Received |
|
2025-02-26 09:16 |
|
Peer-Review Started |
|
2025-02-26 09:17 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2025-03-11 00:03 |
|
Revised |
|
2025-03-14 10:37 |
|
Second Decision |
|
2025-04-11 02:39 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2025-04-11 06:35 |
|
Articles in Press |
|
2025-04-11 06:35 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-05-07 07:51 |
|
Publish the Manuscript Online |
|
2025-05-28 07:32 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Harnessing traditional medicine and biomarker-driven approaches to counteract Trichostatin A-induced esophageal cancer progression
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Heng-Rui Liu |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Heng-Rui Liu, PhD, Cancer Research Institute, Jinan University, Zhongshan Second Road, Yuexiu District, Guangzhou 518000, Guangdong Province, China. lh@yinuobiomedical.cn |
| Key Words |
Traditional Chinese medicine; biomarkers; Esophageal squamous cell carcinoma; Epithelial-mesenchymal transition |
| Core Tip |
Trichostatin A (TSA), a histone deacetylase inhibitor (HDACi), paradoxically promotes esophageal squamous cell carcinoma (ESCC) progression via the BRD4/c-Myc/endoplasmic reticulum stress pathway. Traditional medicine-derived compounds like berberine, curcumin, and resveratrol may counteract these oncogenic effects by modulating epigenetic regulators. Additionally, histone acetylation markers, particularly acetylated histone H3, hold promise as predictive biomarkers for ESCC progression and HDACi therapy response. Integrating biomarker-driven approaches with natural compounds may enhance ESCC treatment efficacy while mitigating HDACi-associated risks. |
| Publish Date |
2025-05-28 07:32 |
| Citation |
<p>Liu HR. Harnessing traditional medicine and biomarker-driven approaches to counteract Trichostatin A-induced esophageal cancer progression. <i>World J Gastroenterol</i> 2025; 31(20): 106443</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i20/106443.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i20.106443 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
