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11/19/2025 5:57:33 AM | Browse: 3 | Download: 5
Publication Name World Journal of Transplantation
Manuscript ID 106444
Country United States
Received
2025-02-28 13:04
Peer-Review Started
2025-02-28 13:04
To Make the First Decision
Return for Revision
2025-03-20 07:24
Revised
2025-03-30 15:44
Second Decision
2025-04-18 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-18 07:47
Articles in Press
2025-04-18 07:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-22 04:06
Publish the Manuscript Online
2025-11-19 05:57
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Outcomes and complications of combined heart-liver transplantation in patients with failing Fontan physiology: A systematic review
Manuscript Source Invited Manuscript
All Author List Muhammad Shahzil, Ume Habiba, Mariyah Zainab Irfan, Muhammad Ahmad Qureshi, Muhammad Saad Faisal, Talha Kashif, Ali Akram Qureshi, Hassam Ali, Vinay Jahagirdar and Rakesh Vinayek
ORCID
Author(s) ORCID Number
Hassam Ali http://orcid.org/0000-0001-5546-9197
Vinay Jahagirdar http://orcid.org/0000-0001-6685-1033
Funding Agency and Grant Number
Corresponding Author Hassam Ali, MD, Division of Gastroenterology, Hepatology and Nutrition, East Carolina University/Brody School of Medicine, 2100 statonsburg rg, Greenville, North Carolina 27858, United States. hassamali155@gmail.com
Key Words Fontan procedure; Heart defects; Congenital; Heart transplantation; Liver transplantation; Multi-organ failure
Core Tip This systematic review analyzes outcomes and complications associated with combined heart-liver transplantation (CHLT) in patients with failing Fontan physiology, a condition resulting from single-ventricle congenital heart disease palliated by the Fontan procedure. CHLT demonstrates a survival advantage over isolated heart transplantation, with significantly lower mortality and shorter ischemic times, while maintaining comparable perioperative outcomes. The findings emphasize the importance of multidisciplinary care, careful patient selection, and surgical expertise. Future prospective studies are needed to refine selection criteria and improve long-term survival in this high-risk population.
Publish Date 2025-11-19 05:57
Citation <p>Shahzil M, Habiba U, Irfan MZ, Qureshi MA, Faisal MS, Kashif T, Qureshi AA, Ali H, Jahagirdar V, Vinayek R. Outcomes and complications of combined heart-liver transplantation in patients with failing Fontan physiology: A systematic review. <i>World J Transplant</i> 2025; 15(4): 106444</p>
URL https://www.wjgnet.com/2220-3230/full/v15/i4/106444.htm
DOI https://dx.doi.org/10.5500/wjt.v15.i4.106444
Full Article (PDF) WJT-15-106444-with-cover.pdf
PRISMA 2009 Checklist 106444-PRISMA-2009-Checklist.pdf
Manuscript File 106444_Auto_Edited_073429.docx
Answering Reviewers 106444-answering-reviewers.pdf
Audio Core Tip 106444-audio.mp3
Biostatistics Review Certificate 106444-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 106444-conflict-of-interest-statement.pdf
Copyright License Agreement 106444-copyright-assignment.pdf
Supplementary Material 106444-supplementary-material.pdf
Peer-review Report 106444-peer-reviews.pdf
Scientific Misconduct Check 106444-scientific-misconduct-check.png
Scientific Editor Work List 106444-scientific-editor-work-list.pdf
CrossCheck Report 106444-crosscheck-report.pdf