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Articles Published Processes
7/18/2025 3:29:37 PM | Browse: 4 | Download: 47
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Received |
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2025-03-03 14:49 |
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Peer-Review Started |
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2025-03-03 14:50 |
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To Make the First Decision |
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Return for Revision |
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2025-04-08 04:57 |
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Revised |
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2025-04-11 16:32 |
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Second Decision |
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2025-05-07 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-07 13:19 |
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Articles in Press |
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2025-05-07 13:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-05-12 21:54 |
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Typeset the Manuscript |
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2025-07-03 01:56 |
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Publish the Manuscript Online |
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2025-07-18 15:29 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Observational Study |
| Article Title |
Diagnostic utility of sepsis screening tools, procalcitonin, and C-reactive protein in nosocomial fever of unknown origin
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shashikant Saini, Sapna Pahil, Ritin Mohindra, Naresh Sachdeva, Navneet Sharma and Ashok K Pannu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ashok K Pannu, Additional Professor, MD, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, 4th Floor, F Block, Chandigarh 160012, India. gawaribacchi@gmail.com |
| Key Words |
Critical care; Fever of unknown origin; Nosocomial; Sepsis; Screening tools; Procalcitonin; C-reactive protein |
| Core Tip |
Nosocomial fever of unknown origin is a frequent and complex challenge in critically ill patients, requiring prompt differentiation between infectious and non-infectious causes. This study evaluates the diagnostic performance of sepsis screening tools, procalcitonin, and C-reactive protein at fever onset. Findings reveal limited utility of all sepsis tools. Procalcitonin shows modest accuracy, while C-reactive protein is unreliable. Given the associated high mortality, this study emphasizes the importance of a structured, systematic evaluation over empirical antibiotic use, and highlights the need for advanced diagnostic modalities to improve infection detection. |
| Publish Date |
2025-07-18 15:29 |
| Citation |
<p>Saini S, Pahil S, Mohindra R, Sachdeva N, Sharma N, Pannu AK. Diagnostic utility of sepsis screening tools, procalcitonin, and C-reactive protein in nosocomial fever of unknown origin. <i>World J Crit Care Med</i> 2025; 14(3): 106496</p> |
| URL |
https://www.wjgnet.com/2220-3141/full/v14/i3/106496.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v14.i3.106496 |
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