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Articles Published Processes
8/26/2015 11:07:00 AM | Browse: 1375 | Download: 1882
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Received |
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2014-04-11 21:30 |
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Peer-Review Started |
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2014-04-12 15:44 |
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To Make the First Decision |
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2014-05-14 13:46 |
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Return for Revision |
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2014-08-19 19:29 |
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Revised |
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2015-03-13 09:27 |
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Second Decision |
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2015-05-15 16:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-05-28 18:13 |
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Articles in Press |
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2015-05-28 18:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-08-14 15:29 |
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Publish the Manuscript Online |
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2015-08-26 11:07 |
| ISSN |
1949-8454 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Review |
| Article Title |
Roles of the canonical myomiRs miR-1, -133 and -206 in cell development and disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Keith Richard Mitchelson and Wen-Yan Qin |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National High-tech Program of China |
2006AA020701 |
| National High-tech Program of China |
2009AA022701 |
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| Corresponding Author |
Dr. Keith Richard Mitchelson, National Engineering Research Centre for Beijing Biochip Technology, 18 Life Science Parkway, Zhonghuan Life Science Park, Beijing 102206, China. keith_mitchelson@hotmail.com |
| Key Words |
Muscle microRNAs; MiR-1; MiR-206; MiR-133a; MiR-133b; Cell development; Cancer |
| Core Tip |
The roles of the canonical muscle-associated microRNAs are reviewed, including microRNA families miR-1 and miR-133, and single miR-206, which are collectively known as the “myomiRs”. The myomiRs act at the crossroads of the molecular regulation of muscle cells, linking between pathways for cell differentiation, development and maintenance, but also potentiate aberrant cell growth in numerous non-muscle cancers. Typically myomiRs are downregulated in cancers, but some myomiRs are upregulated in a few cancers, yet each dysregulation event advances tumor progression. The review examines normal and disease-linked molecular changes associated with the myomiRs, and collates the extensive literature into accessible tables. |
| Publish Date |
2015-08-26 11:07 |
| Citation |
Mitchelson KR, Qin WY. Roles of the canonical myomiRs miR-1, -133 and -206 in cell development and disease. World J Biol Chem 2015; 6(3): 162-208 |
| URL |
http://www.wjgnet.com/1949-8454/full/v6/i3/162.htm |
| DOI |
http://dx.doi.org/10.4331/wjbc.v6.i3.162 |
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