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Articles Published Processes
7/10/2025 3:52:25 AM | Browse: 7 | Download: 43
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Received |
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2025-03-03 16:46 |
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Peer-Review Started |
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2025-03-03 16:46 |
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To Make the First Decision |
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Return for Revision |
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2025-03-13 09:47 |
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Revised |
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2025-03-21 08:43 |
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Second Decision |
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2025-04-07 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-07 07:10 |
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Articles in Press |
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2025-04-07 07:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-04-11 06:29 |
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Typeset the Manuscript |
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2025-06-18 14:33 |
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Publish the Manuscript Online |
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2025-07-10 03:52 |
ISSN |
2220-3206 (online) |
Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, General & Internal |
Manuscript Type |
Editorial |
Article Title |
Mechanisms of cognitive impairment in arterial hypertension
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Manuscript Source |
Invited Manuscript |
All Author List |
Stanislav Nikolaevich Kotlyarov |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Stanislav Nikolaevich Kotlyarov, PhD, Professor, Department of Nurse, Ryazan State Medical University, 9 Vysokovoltnaya, Ryazan 390005, Russia. skmr1@yandex.ru |
Key Words |
Arterial hypertension; Cognitive impairment; Blood-brain barrier; Neuroinflammation; Insulin resistance; Type 3 diabetes hypothesis |
Core Tip |
Arterial hypertension contributes to the development of cognitive impairment through several direct and indirect mechanisms involving hemodynamic, structural, immune, and metabolic abnormalities. There is a U-shaped relationship between blood pressure and the risk of cognitive impairment: that is, both high and low blood pressure can contribute to hemodynamic disturbances in the brain and its structural and functional impairments. Target organ damage in arterial hypertension and comorbidities, including metabolic disorders, are important for the development of cognitive impairment. In this regard, correction of risk factors and maintenance of blood pressure in the target range may be useful for the prevention of cognitive impairment. |
Publish Date |
2025-07-10 03:52 |
Citation |
<p>Kotlyarov SN. Mechanisms of cognitive impairment in arterial hypertension. <i>World J Psychiatry</i> 2025; 15(7): 106597</p> |
URL |
https://www.wjgnet.com/2220-3206/full/v15/i7/106597.htm |
DOI |
https://dx.doi.org/10.5498/wjp.v15.i7.106597 |
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