Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	106604
Country	Italy

Received	2025-03-10 09:02
Peer-Review Started	2025-03-11 00:23
To Make the First Decision
Return for Revision	2025-04-09 12:51
Revised	2025-04-17 15:58
Second Decision	2025-05-23 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-24 01:39
Articles in Press	2025-05-24 01:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-06-04 01:31
Publish the Manuscript Online	2025-06-11 06:21

ISSN	1948-5190 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Sedation in endoscopy: Current practices and future innovations
Manuscript Source	Invited Manuscript
All Author List	Angelo Bruni, Giovanni Barbara, Alessandro Vitello, Giovanni Marasco and Marcello Maida
ORCID	Author(s) ORCID Number Angelo Bruni http://orcid.org/0009-0002-0895-1225 Giovanni Barbara http://orcid.org/0000-0001-9745-0726 Alessandro Vitello http://orcid.org/0000-0001-9099-9468 Giovanni Marasco http://orcid.org/0000-0001-7167-8773 Marcello Maida http://orcid.org/0000-0002-4992-9289
Funding Agency and Grant Number
Corresponding Author	Marcello Maida, MD, Professor, Department of Medicine and Surgery, University of Enna ‘Kore’, Piazza dell’Università 1, Enna 94100, Sicilia, Italy. marcello.maida@unikore.it
Key Words	Etomidate; Propofol; Remimazolam; Endoscopy sedation; Gastrointestinal endoscopy; Sedation monitoring; Target-controlled infusion
Core Tip	In light of the increasing complexity of endoscopic procedures such as endoscopic retrograde cholangiopancreatography, interventional endoscopic ultrasound, and endoscopic submucosal dissection, stable and reversible sedation regimens, exemplified by etomidate-propofol or emerging agents like remimazolam, hold promise for balancing patient comfort, procedural efficacy, and minimal hemodynamic compromise. The study by Luo et al demonstrates that combining etomidate with propofol target-controlled infusion can reduce sedation-related hypotension, speed induction, and improve safety in routine bidirectional endoscopy.
Publish Date	2025-06-11 06:21
Citation	<p>Bruni A, Barbara G, Vitello A, Marasco G, Maida M. Sedation in endoscopy: Current practices and future innovations. <i>World J Gastrointest Endosc</i> 2025; 17(6): 106604</p>
URL	https://www.wjgnet.com/1948-5190/full/v17/i6/106604.htm
DOI	https://dx.doi.org/10.4253/wjge.v17.i6.106604

Full Article (PDF)	WJGE-17-106604-with-cover.pdf
Manuscript File	106604_Auto_Edited_063345.docx
Answering Reviewers	106604-answering-reviewers.pdf
Audio Core Tip	106604-audio.m4a
Conflict-of-Interest Disclosure Form	106604-conflict-of-interest-statement.pdf
Copyright License Agreement	106604-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	106604-non-native-speakers.pdf
Peer-review Report	106604-peer-reviews.pdf
Scientific Misconduct Check	106604-scientific-misconduct-check.png
Scientific Editor Work List	106604-scientific-editor-work-list.pdf
CrossCheck Report	106604-crosscheck-report.pdf