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Articles Published Processes
8/14/2025 5:49:30 AM | Browse: 32 | Download: 159
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Received |
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2025-03-03 03:29 |
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Peer-Review Started |
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2025-03-03 03:29 |
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First Decision by Editorial Office Director |
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2025-03-14 09:18 |
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Return for Revision |
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2025-03-14 09:18 |
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Revised |
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2025-03-27 13:02 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-04-03 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-04-03 06:51 |
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Articles in Press |
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2025-04-03 06:51 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-01 07:33 |
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Publish the Manuscript Online |
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2025-08-14 05:49 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Fatty acid-binding protein 4 as a biomarker for colon adenocarcinoma risk and prognosis: Challenges and future directions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Si-Rui Wang, Ting-Lan Cao and Hui-Zhong Jiang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hui-Zhong Jiang, PhD, Professor, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 11 North Third Ring Road East, Beijing 100007, China. jianghz93@126.com |
| Key Words |
Fatty acid-binding protein 4; Colon adenocarcinoma; Mendelian randomization; Machine learning; Deep learning; Multiple targets |
| Core Tip |
Fatty acid-binding protein 4 (FABP4) is a promising biomarker and potential therapeutic target for colon adenocarcinoma diagnosis and prognosis. Our letter calls for a stronger biological rationale for FABP4’s role and advocates using Mendelian randomization to confirm its causal links. Incorporating machine learning and deep learning can yield more precise prognostic models. We also propose exploring multi-target strategies related to FABP4 and encourage future studies to combine experimental validation to reduce bioinformatics false positives. This allows us to elucidate underlying molecular biological mechanisms, offering fresh insights for personalized colon adenocarcinoma treatment. |
| Publish Date |
2025-08-14 05:49 |
| Citation |
Wang SR, Cao TL, Jiang HZ. Fatty acid-binding protein 4 as a biomarker for colon adenocarcinoma risk and prognosis: Challenges and future directions. World J Gastrointest Oncol 2025; 17(8): 106621 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i8/106621.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i8.106621 |
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