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Articles Published Processes
8/8/2025 9:09:11 AM | Browse: 15 | Download: 97
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Received |
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2025-03-06 09:18 |
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Peer-Review Started |
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2025-03-06 09:18 |
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To Make the First Decision |
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Return for Revision |
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2025-05-07 02:43 |
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Revised |
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2025-06-06 06:13 |
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Second Decision |
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2025-07-07 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-07 08:03 |
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Articles in Press |
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2025-07-07 08:03 |
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Publication Fee Transferred |
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2025-06-13 08:57 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-04 02:19 |
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Publish the Manuscript Online |
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2025-08-08 09:09 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Therapeutic efficacy of thiocolchicoside-nonsteroidal anti-inflammatory drug combination in pain management: A systematic review and cross-sectional real-world study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Arnab Karmakar, Akash Jaiswal, Soham Mandal, Afroz Ahmed Khan and Monjori Mitra |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| CORONA Remedies Limited |
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| Corresponding Author |
Monjori Mitra, Professor, Visiting Professor, Department of Pediatrics, Institute of Child Health, 11 Biresh Guha Street, Kolkata 700017, West Bengal, India. monjorimr@gmail.com |
| Key Words |
Thiocolchicoside; Nonsteroidal anti-inflammatory drugs; Muscle spasms; Low back pain; Muscle relaxants; Combination therapy; Pain management |
| Core Tip |
This systematic review demonstrates the enhanced therapeutic efficacy of combining thiocolchicoside (TCC) with nonsteroidal anti-inflammatory drugs (NSAIDs) for pain management, supported by real-world data from 156713 patients. Our analysis revealed that combination therapy provided superior pain relief, improved functional outcomes, and increased patient satisfaction compared to NSAID monotherapy, without a significant rise in adverse events. Notably, patients receiving the combination were significantly more likely to achieve clinically meaningful pain reduction. These findings support the combined use of TCC and NSAIDs in clinical practice, particularly for musculoskeletal and postoperative pain, to optimize patient outcomes and recovery. |
| Publish Date |
2025-08-08 09:09 |
| Citation |
<p>Karmakar A, Jaiswal A, Mandal S, Khan AA, Mitra M. Therapeutic efficacy of thiocolchicoside-nonsteroidal anti-inflammatory drug combination in pain management: A systematic review and cross-sectional real-world study. <i>World J Orthop</i> 2025; 16(8): 106769</p> |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i8/106769.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i8.106769 |
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