| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Two-week treatment with proton pump inhibitor is sufficient for healing post endoscopic submucosal dissection ulcers
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Makoto Arai, Tomoaki Matsumura, Kenichiro Okimoto, Arata Oyamada, Keiko Saito, Shoko Minemura, Daisuke Maruoka, Takeshi Tanaka, Tomoo Nakagawa, Tatsuro Katsuno and Osamu Yokosuka |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Daiichi Sankyo Co., Ltd. |
|
| AstraZeneca Co., Ltd. |
|
| Otsuka Pharmaceutical Co., Ltd |
To Yokosuka O |
| Daiichi Sankyo, AstraZeneca |
To Arai M |
|
| Corresponding Author |
Makoto Arai
Department of Gastroenterology and Nephrology (K1)
Graduate School of Medicine, Chiba University
Inohana 1-8-1, Chiba-City, 260-8670, Japan
|
| Key Words |
Proton pump inhibitor; Endoscopic submucosal dissection; Esomeprazole; Rebamipide; Randomized control trial |
| Core Tip |
Patients who underwent ESD for gastric cancer were randomized to two groups and treated with esomeprazole 20 mg per day for 4 weeks (4W group) or 2 weeks (2W group). At 4 weeks after ESD, we measured the size of the artificial ulcers by endoscopy. For patients with ulcers in the healing stage at 4 weeks, the ulcer healing rate in the 2W and 4W groups were 94.9 ± 3.6% vs. 94.3 ± 6.9%, respectively, with no statistical difference. |
| Publish Date |
2014-11-20 20:51 |
| Citation |
Arai M, Matsumura T, Okimoto K, Oyamada A, Saito K, Minemura S, Maruoka D, Tanaka T, Nakagawa T, Katsuno T, Yokosuka O. Two-week treatment with proton pump inhibitor is sufficient for healing post endoscopic submucosal dissection ulcers. World J Gastroenterol 2014; 20(43): 16318-16322 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i43/16318.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i43.16318 |
