Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	106783
Country	China

Received	2025-04-18 09:16
Peer-Review Started	2025-04-18 09:16
To Make the First Decision
Return for Revision	2025-05-13 12:05
Revised	2025-05-14 14:31
Second Decision	2025-07-07 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-07 07:40
Articles in Press	2025-07-07 07:40
Publication Fee Transferred	2025-05-22 07:23
Edit the Manuscript by Language Editor	2025-07-11 15:49
Typeset the Manuscript	2025-08-01 02:40
Publish the Manuscript Online	2025-08-14 05:49

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Qige San regulates paclitaxel resistance in esophageal cancer by targeting ferroptosis
Manuscript Source	Unsolicited Manuscript
All Author List	Jie Song, Wen-Ying Guo and Le-Bo Sun
ORCID	Author(s) ORCID Number Le-Bo Sun http://orcid.org/0009-0004-3171-963X
Funding Agency and Grant Number	Funding Agency Grant Number Zhejiang Traditional Chinese Medicine Administration 2024ZL944
Corresponding Author	Le-Bo Sun, Department of Cardiothoracic Surgery, Ningbo Medical Center Lihuili Hospital of Ningbo University, No. 57 Xingning Road, Ningbo 315041, Zhejiang Province, China. sunlebo0910@163.com
Key Words	Esophageal cancer; Paclitaxel resistance; Qige San; Network pharmacology; Ferroptosis
Core Tip	Abnormal iron metabolism plays critical role in paclitaxel-resistant of esophageal cancer cells. Qige San (QG) is a traditional Chinese herbal formula that reported to improve short-term therapeutic effects of esophageal cancer. To investigate the effects and regulatory mechanisms involved in QG-targeted paclitaxel-resistant esophageal cancer cells. QG could repress the resistance of esophageal cancer cells to paclitaxel via targeting PI3K signaling pathway.
Publish Date	2025-08-14 05:49
Citation	<p>Song J, Guo WY, Sun LB. Qige San regulates paclitaxel resistance in esophageal cancer by targeting ferroptosis. <i>World J Gastrointest Oncol</i> 2025; 17(8): 106783</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i8/106783.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i8.106783

Full Article (PDF)	WJGO-17-106783-with-cover.pdf
Manuscript File	106783_Auto_Edited_065858.docx
Answering Reviewers	106783-answering-reviewers.pdf
Audio Core Tip	106783-audio.mp3
Biostatistics Review Certificate	106783-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	106783-conflict-of-interest-statement.pdf
Copyright License Agreement	106783-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	106783-foundation-statement.pdf
Institutional Review Board Approval Form or Document	106783-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	106783-non-native-speakers.pdf
Supplementary Material	106783-supplementary-material.pdf
Peer-review Report	106783-peer-reviews.pdf
Scientific Misconduct Check	106783-scientific-misconduct-check.png
Scientific Editor Work List	106783-scientific-editor-work-list.pdf
CrossCheck Report	106783-crosscheck-report.pdf