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9/15/2025 8:37:54 AM | Browse: 188 | Download: 70
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 106801
Country United States
Received
2025-03-07 10:07
Peer-Review Started
2025-03-07 10:08
To Make the First Decision
Return for Revision
2025-04-02 10:53
Revised
2025-04-09 14:26
Second Decision
2025-04-18 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-18 06:45
Articles in Press
2025-04-18 06:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-02 06:26
Publish the Manuscript Online
2025-09-15 08:37
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Letter to the Editor
Article Title Postoperative immune checkpoint inhibitors plus anti-angiogenesis for hepatitis B virus-associated hepatocellular carcinoma: Analyzing the evidence and future prospects
Manuscript Source Invited Manuscript
All Author List Arunkumar Krishnan and Diptasree Mukherjee
ORCID
Author(s) ORCID Number
Arunkumar Krishnan http://orcid.org/0000-0002-9452-7377
Diptasree Mukherjee http://orcid.org/0000-0002-8962-2759
Funding Agency and Grant Number
Corresponding Author Arunkumar Krishnan, MD, Department of Supportive Oncology, Atrium Health Levine Cancer, 1021 Morehead Medical Drive, Charlotte, NC 28204, United States. dr.arunkumar.krishnan@gmail.com
Key Words Adverse events; Biomarkers; Bias; Confounders; Hepatitis B virus; Hepatocellular carcinoma; Postoperative combined therapy; Immunotherapy; Follow-up
Core Tip A recent study by Lu et al examined postoperative combined therapy (PCT) for hepatitis B virus-associated hepatocellular carcinoma (HBV-HCC). While the findings provide important insights, it is essential to acknowledge several significant limitations. These include the potential for selection bias, a small sample size, and an insufficient focus on monitoring hepatitis B virus reactivation in detail. Future research should prioritize prospective, randomized controlled trials and adopt biomarker-driven approaches to advance the knowledge of the efficacy and safety of PCT. Moreover, extending follow-up periods and fostering global collaboration could enhance treatment outcomes and more effective patient care strategies in managing HBV-HCC.
Publish Date 2025-09-15 08:37
Citation <p>Krishnan A, Mukherjee D. Postoperative immune checkpoint inhibitors plus anti-angiogenesis for hepatitis B virus-associated hepatocellular carcinoma: Analyzing the evidence and future prospects. <i>World J Gastrointest Oncol</i> 2025; 17(9): 106801</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i9/106801.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i9.106801
Full Article (PDF) WJGO-17-106801-with-cover.pdf
Manuscript File 106801_Auto_Edited_070804.docx
Answering Reviewers 106801-answering-reviewers.pdf
Audio Core Tip 106801-audio.mp3
Conflict-of-Interest Disclosure Form 106801-conflict-of-interest-statement.pdf
Copyright License Agreement 106801-copyright-assignment.pdf
Peer-review Report 106801-peer-reviews.pdf
Scientific Editor Work List 106801-scientific-editor-work-list.pdf
CrossCheck Report 106801-crosscheck-report.pdf