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Articles Published Processes
7/15/2025 8:26:20 AM | Browse: 5 | Download: 37
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Received |
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2025-03-10 08:51 |
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Peer-Review Started |
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2025-03-11 00:19 |
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To Make the First Decision |
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Return for Revision |
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2025-03-20 08:12 |
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Revised |
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2025-03-26 03:48 |
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Second Decision |
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2025-05-06 07:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-22 08:30 |
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Articles in Press |
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2025-05-22 08:30 |
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Publication Fee Transferred |
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2025-04-03 06:02 |
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Edit the Manuscript by Language Editor |
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2025-05-27 19:38 |
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Typeset the Manuscript |
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2025-06-27 01:06 |
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Publish the Manuscript Online |
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2025-07-15 08:26 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Lactobacillus rhamnosus LRa05 on glycemic control and gut microbiota in patients with type 2 diabetes
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lin Geng, Ting-Ting Sun, Wen-Bo Xia, Yin Qin, Di Huo and Guang-Jing Qu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Guang-Jing Qu, Department of Second Inpatient, The First Affiliated Hospital of Harbin Medical University, No. 23 Post Street, Nangang District, Harbin, 150001, China, Harbin 150001, Heilongjiang Province, China. quguangjing2022@126.com |
| Key Words |
Lactobacillus rhamnosus; Type 2 diabetes; Glycated hemoglobin; Gut microbiota |
| Core Tip |
Lactobacillus rhamnosus LRa05 is a probiotic that has shown potential in managing type 2 diabetes by improving glycemic control and gut microbiota composition. In a study involving 76 participants over 12 weeks, those who consumed LRa05 experienced significant reductions in fasting blood glucose levels and improved lipid profiles, particularly an increase in high-density lipoprotein cholesterol. The probiotic also positively influenced gut health by promoting beneficial bacteria such as Bifidobacterium while reducing potentially harmful Bacillota levels. Although there were no notable changes in insulin sensitivity or inflammation markers, the overall findings suggest that LRa05 could play a crucial role in diabetes management. These results highlight the importance of gut health in metabolic conditions and encourage further research to explore the long-term benefits and mechanisms of probiotics in diabetes care. Integrating probiotics like LRa05 into dietary strategies may enhance health outcomes for individuals with type 2 diabetes. |
| Publish Date |
2025-07-15 08:26 |
| Citation |
<p>Geng L, Sun TT, Xia WB, Qin Y, Huo D, Qu GJ. Lactobacillus rhamnosus LRa05 on glycemic control and gut microbiota in patients with type 2 diabetes. <i>World J Diabetes</i> 2025; 16(7): 106821</p> |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i7/106821.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i7.106821 |
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