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1/15/2026 8:12:51 AM | Browse: 1 | Download: 1
Publication Name World Journal of Cardiology
Manuscript ID 106885
Country Russia
Received
2025-03-10 05:50
Peer-Review Started
2025-03-10 05:51
First Decision by Editorial Office Director
2025-05-17 08:45
Return for Revision
2025-05-17 08:45
Revised
2025-05-30 08:26
Publication Fee Transferred
Second Decision by Editor
2025-11-25 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-25 12:46
Articles in Press
2025-11-25 12:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-31 09:12
Publish the Manuscript Online
2026-01-15 08:12
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Minireviews
Article Title Comparative characteristics of in vitro models for studying angiogenesis in cardiovascular disease
Manuscript Source Invited Manuscript
All Author List Anastasia Kalinina, Nina Mzhavanadze, Roman Kalinin and Igor Suchkov
ORCID
Author(s) ORCID Number
Nina Mzhavanadze http://orcid.org/0000-0001-5437-1112
Roman Kalinin http://orcid.org/0000-0002-0817-9573
Igor Suchkov http://orcid.org/0000-0002-1292-5452
Funding Agency and Grant Number
Corresponding Author Nina Mzhavanadze, Department of cardiovascular, endovascular surgery and diagnostic radiology, Ryazan State Medical University, Vysokovoltnaya, 9, Ryazan 390026, Russia. nina_mzhavanadze@mail.ru
Key Words Angiogenesis; In vitro models; Cell technologies; Cell cultures; Endothelial cells
Core Tip Experimental angiogenesis research is rapidly evolving in cardiovascular medicine. In vitro models offer precise control and stable experimental conditions with favorable cost-effectiveness compared with ex vivo and in vivo approaches. Limitations include incomplete reproduction of physiological conditions, particularly in 2D systems. Wider implementation of 3D culture, microfluidic platforms, and artificial intelligence should be considered to achieve more comprehensive and physiologically relevant studies of angiogenesis despite greater complexity and cost.
Publish Date 2026-01-15 08:12
Citation

Kalinina A, Mzhavanadze N, Kalinin R, Suchkov I. Comparative characteristics of in vitro models for studying angiogenesis in cardiovascular disease. World J Cardiol 2026; 18(1): 106885

URL https://www.wjgnet.com/1949-8462/full/v18/i1/106885.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i1.106885
Full Article (PDF) WJC-18-106885-with-cover.pdf
Manuscript File 106885_Auto_Edited_090219.docx
Answering Reviewers 106885-answering-reviewers.pdf
Audio Core Tip 106885-audio.mp3
Conflict-of-Interest Disclosure Form 106885-conflict-of-interest-statement.pdf
Copyright License Agreement 106885-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 106885-non-native-speakers.pdf
Peer-review Report 106885-peer-reviews.pdf
Scientific Misconduct Check 106885-scientific-misconduct-check.png
Scientific Editor Work List 106885-scientific-editor-work-list.pdf
CrossCheck Report 106885-crosscheck-report.pdf