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8/26/2025 10:18:26 AM | Browse: 60 | Download: 91
Publication Name World Journal of Psychiatry
Manuscript ID 106906
Country China
Received
2025-04-15 09:33
Peer-Review Started
2025-04-15 09:33
To Make the First Decision
Return for Revision
2025-05-13 10:36
Revised
2025-06-02 15:58
Second Decision
2025-07-09 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-09 07:33
Articles in Press
2025-07-09 07:33
Publication Fee Transferred
2025-07-03 04:06
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-15 06:38
Publish the Manuscript Online
2025-08-26 10:18
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Retrospective Study
Article Title Depressive state on cardiac remodeling and left ventricular function in chronic heart failure: A retrospective study
Manuscript Source Unsolicited Manuscript
All Author List Bo Gao, Yun-Fan Gao, Meng-Ting Chu and Ke-Fang Yuan
ORCID
Author(s) ORCID Number
Ke-Fang Yuan http://orcid.org/0009-0009-0915-7139
Funding Agency and Grant Number
Corresponding Author Ke-Fang Yuan, Department of Cardiovascular Surgery, Hebei Petro China Central Hospital, No. 51 Xinkai Road, Langfang 065000, Hebei Province, China. yuankf198301@163.com
Key Words Chronic heart failure; Depression; Cardiac remodeling; Left ventricular function; Inflammatory response
Core Tip This study highlights a significant link between depression and cardiac remodeling in chronic heart failure (CHF) patients. Depression was associated with lower left ventricular ejection fraction, larger end-diastolic diameter, increased myocardial fibrosis, and elevated inflammatory and neuroendocrine markers. These findings suggest that depressive states exacerbate structural and functional cardiac abnormalities through inflammatory activation, neuroendocrine dysregulation, and enhanced oxidative stress. The results underscore the importance of psychological assessment and targeted management of depression in CHF patients. Addressing depression may mitigate its detrimental cardiovascular effects, offering a potential avenue to improve clinical outcomes and quality of life for patients with heart failure.
Publish Date 2025-08-26 10:18
Citation <p>Gao B, Gao YF, Chu MT, Yuan KF. Depressive state on cardiac remodeling and left ventricular function in chronic heart failure: A retrospective study. <i>World J Psychiatry</i> 2025; 15(9): 106906</p>
URL https://www.wjgnet.com/2220-3206/full/v15/i9/106906.htm
DOI https://dx.doi.org/10.5498/wjp.v15.i9.106906
Full Article (PDF) WJP-15-106906-with-cover.pdf
Manuscript File 106906_Auto_Edited.docx
Answering Reviewers 106906-answering-reviewers.pdf
Audio Core Tip 106906-audio.mp3
Biostatistics Review Certificate 106906-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 106906-conflict-of-interest-statement.pdf
Copyright License Agreement 106906-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 106906-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 106906-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 106906-non-native-speakers.pdf
Peer-review Report 106906-peer-reviews.pdf
Scientific Misconduct Check 106906-scientific-misconduct-check.png
Scientific Editor Work List 106906-scientific-editor-work-list.pdf
CrossCheck Report 106906-crosscheck-report.pdf