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Articles Published Processes
4/27/2025 7:06:39 AM | Browse: 2 | Download: 0
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Received |
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2025-03-11 10:28 |
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Peer-Review Started |
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2025-03-11 10:28 |
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To Make the First Decision |
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Return for Revision |
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2025-03-24 09:55 |
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Revised |
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2025-03-27 10:18 |
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Second Decision |
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2025-04-07 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-07 09:58 |
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Articles in Press |
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2025-04-07 09:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-16 10:26 |
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Publish the Manuscript Online |
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2025-04-27 07:06 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Infectious Diseases |
Manuscript Type |
Editorial |
Article Title |
Tired of the confusion around pleural effusions: Adenosine deaminase detection sets the record straight!
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Manuscript Source |
Invited Manuscript |
All Author List |
Kai-Yan Liu and Xiao-Bing Li |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Xiao-Bing Li, Assistant Professor, MD, PhD, Department of Thoracic Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., No. 116 South Zhuodaoquan Road, Hongshan District, Wuhan 430079, Hubei Province, China. lixiaobing0629@126.com |
Key Words |
Pleural effusion; Pleural inflammation; Diagnosis; Biomarker; Adenosine deaminase |
Core Tip |
Pleural effusion, characterized by the accumulation of fluid in the pleural space, poses significant challenges in clinical practice, particularly in distinguishing inflammatory exudates from non-inflammatory transudates. Adenosine deaminase (ADA), an enzyme primary produced by immune cells, especially lymphocytes, increase in response to inflammatory conditions, including infections such as tuberculosis and malignancies. Elevated ADA levels in pleural have been shown to correlate with inflammatory exudates, making it a valuable biomarker for differentiating between inflammatory and non-inflammatory effusions. Moreover, numerous studies have demonstrated the utility of ADA in inflammation- related pleural effusion syndrome. Recent research has established reference values for the implication of ADA in diagnosing and managing pleural disease. Based on these findings, ADA becomes a reliable, non-invasive marker for early diagnosis and the appropriate treatment of pleural inflammation, ultimately improving patient outcomes. |
Publish Date |
2025-04-27 07:06 |
Citation |
<p>Liu KY, Li XB. Tired of the confusion around pleural effusions: Adenosine deaminase detection sets the record straight!. <i>World J Clin Cases</i> 2025; 13(21): 106945</p> |
URL |
https://www.wjgnet.com/2307-8960/full/v13/i21/106945.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v13.i21.106945 |
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