BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
4/27/2025 7:06:39 AM | Browse: 2 | Download: 0
Publication Name World Journal of Clinical Cases
Manuscript ID 106945
Country China
Received
2025-03-11 10:28
Peer-Review Started
2025-03-11 10:28
To Make the First Decision
Return for Revision
2025-03-24 09:55
Revised
2025-03-27 10:18
Second Decision
2025-04-07 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-07 09:58
Articles in Press
2025-04-07 09:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-04-16 10:26
Publish the Manuscript Online
2025-04-27 07:06
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Editorial
Article Title Tired of the confusion around pleural effusions: Adenosine deaminase detection sets the record straight!
Manuscript Source Invited Manuscript
All Author List Kai-Yan Liu and Xiao-Bing Li
ORCID
Author(s) ORCID Number
Xiao-Bing Li http://orcid.org/0000-0002-3332-0575
Funding Agency and Grant Number
Corresponding Author Xiao-Bing Li, Assistant Professor, MD, PhD, Department of Thoracic Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., No. 116 South Zhuodaoquan Road, Hongshan District, Wuhan 430079, Hubei Province, China. lixiaobing0629@126.com
Key Words Pleural effusion; Pleural inflammation; Diagnosis; Biomarker; Adenosine deaminase
Core Tip Pleural effusion, characterized by the accumulation of fluid in the pleural space, poses significant challenges in clinical practice, particularly in distinguishing inflammatory exudates from non-inflammatory transudates. Adenosine deaminase (ADA), an enzyme primary produced by immune cells, especially lymphocytes, increase in response to inflammatory conditions, including infections such as tuberculosis and malignancies. Elevated ADA levels in pleural have been shown to correlate with inflammatory exudates, making it a valuable biomarker for differentiating between inflammatory and non-inflammatory effusions. Moreover, numerous studies have demonstrated the utility of ADA in inflammation- related pleural effusion syndrome. Recent research has established reference values for the implication of ADA in diagnosing and managing pleural disease. Based on these findings, ADA becomes a reliable, non-invasive marker for early diagnosis and the appropriate treatment of pleural inflammation, ultimately improving patient outcomes.
Publish Date 2025-04-27 07:06
Citation <p>Liu KY, Li XB. Tired of the confusion around pleural effusions: Adenosine deaminase detection sets the record straight!. <i>World J Clin Cases</i> 2025; 13(21): 106945</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i21/106945.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i21.106945
Full Article (PDF) WJCC-13-106945-with-cover.pdf
Manuscript File 106945_Auto_Edited_031930.docx
Answering Reviewers 106945-answering-reviewers.pdf
Audio Core Tip 106945-audio.m4a
Conflict-of-Interest Disclosure Form 106945-conflict-of-interest-statement.pdf
Copyright License Agreement 106945-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 106945-non-native-speakers.pdf
Peer-review Report 106945-peer-reviews.pdf
Scientific Misconduct Check 106945-scientific-misconduct-check.png
Scientific Editor Work List 106945-scientific-editor-work-list.pdf
CrossCheck Report 106945-crosscheck-report.pdf