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Articles Published Processes
3/9/2015 3:58:00 PM | Browse: 1547 | Download: 1691
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Received |
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2014-04-15 10:00 |
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Peer-Review Started |
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2014-04-15 19:36 |
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To Make the First Decision |
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2014-06-10 13:33 |
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Return for Revision |
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2014-06-11 10:33 |
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Revised |
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2014-07-12 13:34 |
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Second Decision |
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2014-08-28 10:00 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-08-28 10:26 |
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Articles in Press |
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2014-08-28 10:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-02-25 11:07 |
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Publish the Manuscript Online |
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2015-03-09 15:58 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, General & Internal |
Manuscript Type |
Observational Study |
Article Title |
Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Christina M Hester, Venkatakrishna R Jala, Morgan GI Langille, Shahid Umar, K Allen Greiner and Bodduluri Haribabu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
University of Kansas Cancer Center |
U54CA154253 |
University of Kansas Clinical Translational Science Program |
CA123245 |
NCI at NIH |
1R01CA138623 |
James Graham Brown Cancer Center, University of Louisville |
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Corresponding Author |
Christina M Hester, PhD, Assistant Professor, Department of Family Medicine Research Division, University of Kansas Medical Center, Kansas City, MS 3064, 3901 Rainbow Boulevard, KS 66160, United States. chester@kumc.edu |
Key Words |
Colorectal cancer; Short chain fatty acids; Racial/ethnic disparities; Butyrate; Microbiota |
Core Tip |
This brief report describes analysis of stool samples from 20 adult participants aged 50 years and above using 16S rRNA pyrosequencing. We found significantly lower short chain fatty acid levels and significantly different microbial profiles in African Americans vs Whites. We also found a significant correlation between the predicted butyrate kinase levels based on 16S rRNA gene abundance and stool levels of butyrate. These results should be useful in future analysis of colorectal cancer incidence and mortality differentials across racial/ethnic groups. |
Publish Date |
2015-03-09 15:58 |
Citation |
Hester CM, Jala VR, Langille MGI, Umar S, Greiner KA, Haribabu B. Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups. World J Gastroenterol 2015; 21(9): 2759-2769 |
URL |
http://www.wjgnet.com/1007-9327/full/v21/i9/2759.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v21.i9.2759 |
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