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Articles Published Processes
7/15/2025 8:26:36 AM | Browse: 105 | Download: 637
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Received |
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2025-03-17 03:43 |
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Peer-Review Started |
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2025-03-18 00:21 |
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First Decision by Editorial Office Director |
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2025-04-03 04:00 |
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Return for Revision |
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2025-04-03 04:00 |
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Revised |
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2025-04-26 05:11 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-06-11 03:28 |
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Second Decision by Editor-in-Chief |
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2025-06-15 14:18 |
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Final Decision by Editorial Office Director |
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2025-06-19 07:56 |
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Articles in Press |
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2025-06-19 07:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-03 00:38 |
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Publish the Manuscript Online |
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2025-07-15 08:26 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Retrospective Study |
| Article Title |
First metatarsophalangeal joint synovial hypertrophy associated with vitamin D status in type 2 diabetes mellitus: An ultrasound-graded study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qing-Shan Li, Xiao-Hui Xiao, Yu-Ying Cai, Xiao-Peng Xiao, Ping-Xiang Hu and Hong Li |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hong Li, MD, Department of Ultrasound, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine (Shenzhen Traditional Chinese Medicine Hospital), No. 1 Fuhua Road, Futian District, Shenzhen 518000, Guangdong Province, China. lihong_echo@163.com |
| Key Words |
Vitamin D; Synovial hypertrophy; Type 2 diabetes mellitus; Metatarsophalangeal joint; Serum 25-hydroxyvitamin D |
| Core Tip |
This study refines a semi-quantitative ultrasound grading system for first metatarsophalangeal joint synovial hypertrophy by introducing a novel subtype that specifically classifies cases of dorsal recess overlying the metatarsal bone, demonstrating high reliability (intra-observer ICC = 0.79; inter-observer ICC = 0.73). We identified a significant inverse, non-linear correlation between serum 25-hydroxyvitamin D levels and synovial hypertrophy severity, with a threshold effect at 23.8 ng/mL. These findings suggest that vitamin D deficiency may contribute to synovial inflammation in T2DM patients and that targeted screening and supplementation could help mitigate joint complications. |
| Publish Date |
2025-07-15 08:26 |
| Citation |
Li QS, Xiao XH, Cai YY, Xiao XP, Hu PX, Li H. First metatarsophalangeal joint synovial hypertrophy associated with vitamin D status in type 2 diabetes mellitus: An ultrasound-graded study. World J Diabetes 2025; 16(7): 107019 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i7/107019.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i7.107019 |
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