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7/23/2025 11:11:02 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 107099
Country India
Received
2025-03-16 05:13
Peer-Review Started
2025-03-16 05:14
To Make the First Decision
Return for Revision
2025-04-02 13:25
Revised
2025-04-23 05:51
Second Decision
2025-05-28 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-05-28 08:32
Articles in Press
2025-05-28 08:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-06-04 18:50
Typeset the Manuscript
2025-07-09 03:11
Publish the Manuscript Online
2025-07-23 11:11
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title TONEFACT: Can even advanced hemorrhoids be treated without surgery? A paradigm shift in the management of hemorrhoids
Manuscript Source Invited Manuscript
All Author List Pankaj Garg, Inna Tulina, Dong-Lin Ren, Kaushik Bhattacharya, Vipul D Yagnik and Garg Mahak
ORCID
Author(s) ORCID Number
Pankaj Garg http://orcid.org/0000-0002-0800-3578
Inna Tulina http://orcid.org/0000-0002-6404-389X
Dong-Lin Ren http://orcid.org/0000-0001-5599-8654
Kaushik Bhattacharya http://orcid.org/0000-0002-4825-9148
Vipul D Yagnik http://orcid.org/0000-0003-4008-6040
Garg Mahak http://orcid.org/0009-0000-3866-3000
Funding Agency and Grant Number
Corresponding Author Pankaj Garg, Department of Colorectal Surgery, Garg Fistula Research Institute, 1042, Sector-15, Panchkula 134113, Haryana, India. drgargpankaj@gmail.com
Key Words Hemorrhoids; Fiber; Water intake; Non-surgical; Conservative management
Core Tip Hemorrhoids are one of the most prevalent disorders. A lot of hemorrhoids patients are operated on, especially in advanced grades (late grade II, grade III & grade IV) and hemorrhoids with uncontrolled bleeding. TONEFACT is a novel treatment that rectifies the root cause of hemorrhoids, thereby stopping the progression and causing the cessation of symptoms (bleeding and thrombosis). Thus, it removes the requirement of surgery in a good proportion of patients who had been advocated surgery. Considering the high prevalence rate of the disease, this amounts to enormous savings in hospital admission and surgical morbidity at the global level.
Publish Date 2025-07-23 11:11
Citation <p>Garg P, Tulina I, Ren DL, Bhattacharya K, Yagnik VD, Mahak G. TONEFACT: Can even advanced hemorrhoids be treated without surgery? A paradigm shift in the management of hemorrhoids. <i>World J Gastrointest Surg</i> 2025; 17(7): 107099</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i7/107099.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i7.107099
Full Article (PDF) WJGS-17-107099-with-cover.pdf
Manuscript File 107099_Auto_Edited_061414.docx
Answering Reviewers 107099-answering-reviewers.pdf
Audio Core Tip 107099-audio.MP3
Conflict-of-Interest Disclosure Form 107099-conflict-of-interest-statement.pdf
Copyright License Agreement 107099-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 107099-non-native-speakers.pdf
Peer-review Report 107099-peer-reviews.pdf
Scientific Misconduct Check 107099-scientific-misconduct-check.png
Scientific Editor Work List 107099-scientific-editor-work-list.pdf
CrossCheck Report 107099-crosscheck-report.pdf