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Articles Published Processes
7/23/2025 11:10:55 AM | Browse: 2 | Download: 0
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Received |
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2025-03-17 04:04 |
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Peer-Review Started |
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2025-03-17 04:04 |
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To Make the First Decision |
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Return for Revision |
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2025-04-14 10:36 |
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Revised |
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2025-04-24 22:30 |
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Second Decision |
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2025-05-28 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-28 08:59 |
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Articles in Press |
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2025-05-28 08:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-08 00:50 |
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Publish the Manuscript Online |
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2025-07-23 11:10 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Multi-omics perspectives for gastrointestinal malignancy: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Thai-Hau Koo, Yi-Lin Lee, Xue-Bin Leong, Firdaus Hayati, Mohd Hazeman Zakaria and Andee Dzulkarnaen Zakaria |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Andee Dzulkarnaen Zakaria, MD, Professor, Department of Surgery, School of Medical Sciences, University Sains Malaysia, Jalan Raja Perempuan Zainab 2, Kubang Kerian, Kota Bharu 16150, Kelantan, Malaysia. andee@usm.my |
| Key Words |
Proteomic; Multi-omics; Gastrointestinal malignancy; Precision oncology; Biomarker discovery; Therapeutic resistance |
| Core Tip |
Gastrointestinal malignancies present substantial diagnostic and therapeutic challenges due to their molecular complexity. This systematic review highlights how comprehensive omics strategies incorporating genomic, transcriptomic, proteomic, and metabolomic data and epigenomics, integrated with machine learning and artificial intelligence, can revolutionize precision oncology. These strategies enable early detection through biomarkers like circulating tumor DNA and extracellular vesicles, enhance risk stratification, and uncover mechanisms of drug resistance and tumor heterogeneity, paving the way for individualized gastrointestinal cancer therapies. |
| Publish Date |
2025-07-23 11:10 |
| Citation |
<p>Koo TH, Lee YL, Leong XB, Hayati F, Zakaria MH, Zakaria AD. Multi-omics perspectives for gastrointestinal malignancy: A systematic review. <i>World J Gastrointest Surg</i> 2025; 17(7): 107110</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i7/107110.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i7.107110 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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