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Articles Published Processes
7/23/2025 11:10:54 AM | Browse: 3 | Download: 0
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Received |
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2025-03-21 09:47 |
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Peer-Review Started |
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2025-03-21 09:47 |
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To Make the First Decision |
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Return for Revision |
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2025-04-08 12:37 |
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Revised |
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2025-04-20 10:57 |
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Second Decision |
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2025-05-28 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-28 09:26 |
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Articles in Press |
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2025-05-28 09:26 |
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Publication Fee Transferred |
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2025-04-24 06:25 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-08 00:51 |
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Publish the Manuscript Online |
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2025-07-23 11:10 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
MicroRNA 195, lactate dehydrogenase 5, phosphatase and tensin homologue in colorectal cancer: Clinicopathology and prognosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zuo Tang and Li-Ming Wen |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Li-Ming Wen, Chief Physician, Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, No. 319 Section 3, Zhongshan Road, Luzhou 646000, Sichuan Province, China. wenlm404@yeah.net |
| Key Words |
Colorectal cancer; MicroRNA 195; Lactate dehydrogenase-5; Phosphatase and tensin homologue; Clinicopathology; Prognosis |
| Core Tip |
Colorectal cancer (CRC) incidence has shown a sustained annual increase with a notable trend toward younger-onset cases, significantly affecting public health. In this retrospective cohort study, we systematically conducted clinical data of 53 CRC patients, performing quantitative comparison of microRNA 195 (miR195), lactate dehydrogenase-5 (LDH-5), and phosphatase and tensin homologue (PTEN) expression profiles between tumor tissues and matched adjacent normal tissues, as well as their correlation with clinicopathological parameters and prognosis. Our findings revealed that reduced miR195 and PTEN expression, coupled high LDH-5 expression exhibited strong mechanistic associations with CRC pathogenesis and disease progression, suggesting that molecular alterations as potential utility as a novel diagnostic indicators for precision oncology applications. |
| Publish Date |
2025-07-23 11:10 |
| Citation |
<p>Tang Z, Wen LM. MicroRNA 195, lactate dehydrogenase 5, phosphatase and tensin homologue in colorectal cancer: Clinicopathology and prognosis. <i>World J Gastrointest Surg</i> 2025; 17(7): 107121</p> |
| URL |
https://www.wjgnet.com/1948-9366/full/v17/i7/107121.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v17.i7.107121 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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