| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Expert Consensus |
| Article Title |
First regional consensus on the management of Helicobacter pylori infection in the Middle East
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ala I Sharara, Fahad I Alsohaibani, Ahmad Alsaegh, Khalid Al Ejji, Sameer Al Awadhi, Peter Malfertheiner, Sherif Karam and Talal Al-Taweel |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| NewBridge Pharmaceuticals |
|
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| Corresponding Author |
Talal Al-Taweel, MD, MRCP, Division of Gastroenterology, Department of Internal Medicine, Jaber Al-Ahmad Hospital, Block 1, King Khalid Bin Abdulaziz Street, Ministries Area 900015, Kuwait. taltaweel@moh.gov.kw |
| Key Words |
Helicobacter pylori; Antibiotic resistance; Consensus guidelines; Gastric cancer; Gut microbiota |
| Core Tip |
This expert consensus comprises comprehensive guidelines for the management of Helicobacter pylori (H. pylori) infection in the Middle East, addressing its diagnosis, treatment, and prevention, with a focus on antibiotic resistance and gut microbiota interactions. Given the rising clarithromycin and fluoroquinolone resistance, this report emphasizes the importance of antibiotic stewardship, routine susceptibility testing, and optimized first-line and rescue therapies. Incorporating regional epidemiological data, this consensus aligns with the recommendations of the Maastricht VI/Florence consensus and proposes tailored strategies to enhance eradication success and reduce the risk of gastric cancer, thereby improving the clinical outcomes and management of H. pylori infection. |
| Publish Date |
2025-07-21 09:42 |
| Citation |
<p>Sharara AI, Alsohaibani FI, Alsaegh A, Al Ejji K, Al Awadhi S, Malfertheiner P, Karam S, Al-Taweel T. First regional consensus on the management of Helicobacter pylori infection in the Middle East. <i>World J Gastroenterol</i> 2025; 31(27): 107138</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i27/107138.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i27.107138 |
