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Articles Published Processes
9/26/2025 8:19:50 AM | Browse: 279 | Download: 113
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Received |
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2025-05-23 11:54 |
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Peer-Review Started |
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2025-05-23 11:54 |
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To Make the First Decision |
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Return for Revision |
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2025-06-17 03:19 |
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Revised |
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2025-06-24 17:25 |
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Second Decision |
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2025-08-19 02:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-08-19 07:35 |
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Articles in Press |
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2025-08-19 07:35 |
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Publication Fee Transferred |
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2025-07-04 08:15 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-12 08:26 |
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Publish the Manuscript Online |
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2025-09-26 08:19 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Depression and anxiety in patients with endometriosis-associated chronic pain: Neuroimmune mechanisms mediated by inflammatory factors
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fan-Chun Yang, Yang Zhou, Shi-Yun Zhang and Rui Ma |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Rui Ma, MD, Department of Obstetrics and Gynecology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, No. 301 Yanchang Middle Road, Jing’an District, Shanghai 200072, China. ruima127@163.com |
| Key Words |
Endometriosis; Chronic pain; Depression; Anxiety; Inflammation; Neuroimmune; Cytokines; Brain-derived neurotrophic factor |
| Core Tip |
Endometriosis-associated chronic pain is frequently accompanied by depression and anxiety, but the underlying mechanisms remain unclear. This study highlights the role of inflammatory biomarkers, including interleukin-6, interleukin-1β, tumor necrosis factor-alpha, C-reactive protein, and brain-derived neurotrophic factor, in mediating these psychological comorbidities. Higher inflammatory marker levels correlate with increased pain severity and psychological distress. These findings suggest a neuroimmune link between endometriosis and mental health conditions, providing potential therapeutic targets. Addressing inflammation may improve both physical and psychological symptoms, emphasizing the need for an integrated treatment approach in managing endometriosis patients. |
| Publish Date |
2025-09-26 08:19 |
| Citation |
<p>Yang FC, Zhou Y, Zhang SY, Ma R. Depression and anxiety in patients with endometriosis-associated chronic pain: Neuroimmune mechanisms mediated by inflammatory factors. <i>World J Psychiatry</i> 2025; 15(10): 107147</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i10/107147.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i10.107147 |
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