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Articles Published Processes
11/19/2025 5:57:39 AM | Browse: 13 | Download: 34
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Received |
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2025-03-17 08:08 |
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Peer-Review Started |
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2025-03-17 08:08 |
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First Decision by Editorial Office Director |
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2025-04-01 05:40 |
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Return for Revision |
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2025-04-01 05:40 |
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Revised |
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2025-04-14 07:47 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-05-19 02:45 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-05-21 14:27 |
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Articles in Press |
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2025-05-21 14:27 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-08-07 15:24 |
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Publish the Manuscript Online |
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2025-11-19 05:57 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Increase in failed swallows from pre- to post-lung transplant esophageal function testing is associated with acute rejection
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Wai-Kit Lo, Pranay Nadella, Natan Feldman, Nirmal Sharma, Hilary J Goldberg and Walter W Chan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Walter W Chan, AGAF, Associate Professor, FACG, MD, Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, United States. wwchan@bwh.harvard.edu |
| Key Words |
Esophageal dysmotility; High-resolution manometry; Ineffective esophageal motility; Failed swallows; Lung transplantation; Acute rejection |
| Core Tip |
Gastroesophageal reflux has been associated with poor outcomes after lung transplantation, though the pathophysiology remains unclear. Lung transplantation itself may modulate this risk through impacts on pulmonary function and intrathoracic pressures, which alters esophageal motility to affect bolus clearance and reflux severity. Our study demonstrated that increased failed swallows from pre- to post-transplant testing was associated with increased risk of acute rejection after lung transplant, and was inversely correlated with baseline percent-predicted total lung capacity. The physiologic impact of lung transplantation may therefore affect esophageal function and contribute to rejection outcomes, suggesting a need for routine manometric testing in this high-risk patient population. |
| Publish Date |
2025-11-19 05:57 |
| Citation |
Lo WK, Nadella P, Feldman N, Sharma N, Goldberg HJ, Chan WW. Increase in failed swallows from pre- to post-lung transplant esophageal function testing is associated with acute rejection. World J Transplant 2025; 15(4): 107149 |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i4/107149.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i4.107149 |
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