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7/24/2025 9:11:33 AM | Browse: 123 | Download: 402
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Received |
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2025-03-17 03:52 |
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Peer-Review Started |
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2025-03-24 00:11 |
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First Decision by Editorial Office Director |
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2025-04-30 07:34 |
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Return for Revision |
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2025-04-30 07:34 |
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Revised |
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2025-05-11 17:14 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-06-18 05:28 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-06-19 08:53 |
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Articles in Press |
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2025-06-19 08:53 |
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Edit the Manuscript by Language Editor |
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2025-06-26 19:24 |
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Typeset the Manuscript |
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2025-07-16 07:37 |
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Publish the Manuscript Online |
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2025-07-24 09:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Minireviews |
| Article Title |
When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Aisha Al-Battashy and Nouf Al-Farsi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nouf Al-Farsi, Chief Physician, FRCS, MD, Department of Ophthalmology, Sultan Qaboos University, P.O. Box 38 P.C. 123 Al-Khoud, Muscat 123, Oman. noufalfarsi@gmail.com |
| Key Words |
Cytomegalovirus retinitis; Pediatric stem cell transplant; Hematopoietic stem cell transplantation; Cytomegalovirus viremia; Ocular complications; Antiviral therapy; Immune reconstitution; T-cell therapy; Screening protocols |
| Core Tip |
Cytomegalovirus retinitis in pediatric hematopoietic stem cell transplant recipients is a complex and potentially devastating complication, but with early detection and appropriate management, outcomes can be significantly improved. Screening protocols continue to evolve, with the emphasis on identifying high-risk patients during periods of immune reconstitution. Management of cytomegalovirus retinitis in pediatric patients post-hematopoietic stem cell transplant requires a comprehensive approach that balances effective viral suppression with the mitigation of drug-related toxicities. Antiviral therapies, whether systemic, intravitreal, or implantable, remain central to treatment. Adjunctive immunotherapies, particularly adoptive T-cell therapy, offer promising outcomes in refractory cases. Emerging modalities, including high-dose intravitreal regimens and novel antivirals, hold potential for future advancements. Individualized treatment plans, guided by patient-specific risk factors and disease severity, are crucial for optimizing outcomes and preserving vision in this vulnerable population. |
| Publish Date |
2025-07-24 09:11 |
| Citation |
Al-Battashy A, Al-Farsi N. When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients. World J Stem Cells 2025; 17(7): 107153 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i7/107153.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i7.107153 |
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