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Articles Published Processes
2/10/2026 10:35:31 AM | Browse: 15 | Download: 91
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Received |
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2025-03-17 08:38 |
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Peer-Review Started |
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2025-03-25 09:11 |
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First Decision by Editorial Office Director |
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2025-04-14 03:54 |
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Return for Revision |
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2025-04-14 03:54 |
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Revised |
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2025-04-21 20:06 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-07-08 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-08 09:17 |
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Articles in Press |
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2025-07-08 09:17 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-31 03:38 |
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Publish the Manuscript Online |
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2026-02-10 10:35 |
| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Exploring effectiveness of Metronidazole, Bismuth, and Rifaximin in treating small intestinal bacterial overgrowth and irritable bowel syndrome: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Qaim Shah and Jonathan Soldera |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jonathan Soldera, PhD, Learna Ltd. in Association with University of South Wales, Treforest, Cardiff CF37 1DL, United Kingdom. jonathansoldera@gmail.com |
| Key Words |
Small intestinal bacterial overgrowth; Irritable bowel syndrome; Rifaximin; Metronidazole; Bismuth |
| Core Tip |
This study compares the efficacy and safety of Metronidazole, Bismuth, and Rifaximin in managing small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS). Rifaximin showed the greatest clinical benefit, particularly in diarrhea-predominant IBS patients, with minimal side effects. Metronidazole was effective for SIBO but associated with higher gastrointestinal side effects. Bismuth demonstrated some effectiveness, particularly in combination therapies, but was less pronounced than the other two antibiotics. Further research is needed to optimize treatment strategies and assess long-term outcomes. |
| Publish Date |
2026-02-10 10:35 |
| Citation |
Shah Q, Soldera J. Exploring effectiveness of Metronidazole, Bismuth, and Rifaximin in treating small intestinal bacterial overgrowth and irritable bowel syndrome: A systematic review. World J Methodol 2026; 16(1): 107169 |
| URL |
https://www.wjgnet.com/2222-0682/full/v16/i1/107169.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v16.i1.107169 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
