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8/20/2025 8:41:27 AM | Browse: 70 | Download: 179
Publication Name World Journal of Clinical Oncology
Manuscript ID 107208
Country United States
Received
2025-03-18 12:42
Peer-Review Started
2025-03-18 12:43
To Make the First Decision
Return for Revision
2025-04-28 09:18
Revised
2025-05-19 19:50
Second Decision
2025-07-08 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-08 08:52
Articles in Press
2025-07-08 08:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-08-07 06:17
Publish the Manuscript Online
2025-08-20 08:41
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Basic Study
Article Title GPR81 nuclear transportation is critical for cancer growth and progression in lung and other solid cancers
Manuscript Source Unsolicited Manuscript
All Author List LiBang Yang, Thomas Kono, Adam Gilbertsen, Yingming Li, Bo Sun, Blake A Jacobson, Sabine Karam, Scott M Dehm, Craig A Henke and Robert A Kratzke
ORCID
Author(s) ORCID Number
LiBang Yang http://orcid.org/0000-0002-9318-6320
Funding Agency and Grant Number
Corresponding Author LiBang Yang, MD, PhD, Senior Researcher, Department of Medicine, University of Minnesota, 420 Delaware Street, Minneapolis, MN 55455, United States. yangx822@umn.edu
Key Words Solid cancers; GPR81; Nuclear translocation; Proteomics; Chromatin immunoprecipitation sequencing; Ingenuity pathway analysis; Warburg effect; Self-renewal; Invasion
Core Tip Lactate promotes GPR81 expression and nuclear transportation. where GPR81 interacts with nuclear proteins and regulates cancer cell function. Then targeting GPR81 and its nuclear transportation provides an opportunity to develop novel treatments targeting cancers.
Publish Date 2025-08-20 08:41
Citation <p>Yang L, Kono T, Gilbertsen A, Li Y, Sun B, Jacobson BA, Karam S, Dehm SM, Henke CA, Kratzke RA. GPR81 nuclear transportation is critical for cancer growth and progression in lung and other solid cancers. <i>World J Clin Oncol</i> 2025; 16(8): 107208</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i8/107208.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i8.107208
Full Article (PDF) WJCO-16-107208-with-cover.pdf
The ARRIVE Guidelines 107208-The-ARRIVE-Guidelines.pdf
Manuscript File 107208_Auto_Edited_013130.docx
Answering Reviewers 107208-answering-reviewers.pdf
Audio Core Tip 107208-audio.mp3
Biostatistics Review Certificate 107208-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 107208-conflict-of-interest-statement.pdf
Copyright License Agreement 107208-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 107208-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 107208-institutional-review-board-statement.pdf
Supplementary Material 107208-supplementary-material.pdf
Peer-review Report 107208-peer-reviews.pdf
Scientific Misconduct Check 107208-scientific-misconduct-check.png
Scientific Editor Work List 107208-scientific-editor-work-list.pdf
CrossCheck Report 107208-crosscheck-report.pdf