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Articles Published Processes
6/19/2025 8:18:36 AM | Browse: 13 | Download: 120
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Received |
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2025-03-19 11:34 |
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Peer-Review Started |
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2025-03-19 11:34 |
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To Make the First Decision |
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Return for Revision |
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2025-04-09 12:52 |
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Revised |
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2025-04-13 17:36 |
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Second Decision |
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2025-05-15 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-05-18 14:01 |
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Articles in Press |
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2025-05-18 14:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-10 07:00 |
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Publish the Manuscript Online |
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2025-06-19 08:18 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Evidence Review |
| Article Title |
Pancreatic neuroendocrine tumors: A case-based evidence review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Naveena Rikhraj, Cornelius J Fernandez, Vanishri Ganakumar and Joseph M Pappachan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Joseph M Pappachan, Academic Editor, FRCP, MD, MRCP, Professor, Senior Researcher, Faculty of Science,, Manchester Metropolitan University, Manchester, Manchester M15 6BH, Please enter the state or province, United Kingdom. drpappachan@yahoo.co.in |
| Key Words |
Pancreatic neuroendocrine tumour; Somatostatin analog therapy; Insulinoma; Nonfunctional pNET; Metastatic disease; Somatostatin receptor imaging |
| Core Tip |
Pancreatic neuroendocrine tumors (pNETs) are rare neoplasms with variable clinical and pathobiological characteristics posing diagnostic and therapeutic challenges. Mostly nonfunctional with low growth rates, some cases can be functional while others can run an aggressive clinical course. Hormonal, imaging and histological assessments are essential for planning appropriate diagnosis, prognosis and management. Therapeutic strategies depend on the tumor grade, functionality and presence of metastatic disease. Nonfunctioning pNETs very rarely turn functional during the advanced disease course. Presenting a unique nonfunctioning metastatic pNET case, later evolving to an insulinoma, we update the diagnostic, prognostic and management strategies for pNETs in the evidence-based review. |
| Publish Date |
2025-06-19 08:18 |
| Citation |
<p>Rikhraj N, Fernandez CJ, Ganakumar V, Pappachan JM. Pancreatic neuroendocrine tumors: A case-based evidence review. <i>World J Gastrointest Pathophysiol</i> 2025; 16(2): 107265</p> |
| URL |
https://www.wjgnet.com/2150-5330/full/v16/i2/107265.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v16.i2.107265 |
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