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9/24/2025 9:02:12 AM | Browse: 88 | Download: 85
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 107301
Country China
Received
2025-05-28 08:59
Peer-Review Started
2025-05-28 08:59
To Make the First Decision
Return for Revision
2025-06-17 02:49
Revised
2025-06-30 15:46
Second Decision
2025-08-06 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-06 04:34
Articles in Press
2025-08-06 04:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-11 02:31
Publish the Manuscript Online
2025-09-24 09:02
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Retrospective Study
Article Title Diagnostic significance of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography in differentiating Edmondson grade II and III hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Xiao-Bo Niu, Yan-Peng Li, Fang-Fang Chao, Xiao-Li Mei, Xing-Min Han and Rui-Hua Wang
ORCID
Author(s) ORCID Number
Xiao-Bo Niu http://orcid.org/0009-0002-1724-4290
Rui-Hua Wang http://orcid.org/0009-0005-7696-760X
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82171983
Henan Provincial Science and Technology Research Project 242102311089
Corresponding Author Rui-Hua Wang, DM, Department of Nuclear Medicine, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Erqi District, Zhengzhou 450052, Henan Province, China. wangruihua2004@126.com
Key Words Hepatocellular carcinoma; Fluorine-18-fluorodeoxyglucose; Positron emission tomography-computed tomography; Metabolic parameters; Edmondson grading
Core Tip Fluorine-18-fluorodeoxyglucose (18F-FDG)-positron emission tomography/computed tomography technology has established its indispensable position in numerous aspects of liver cancer diagnosis, staging, lymph node metastasis assessment, and prognosis prediction. The hypermetabolic nature of malignant cells, induced by accelerated glycolysis, increases 18F-FDG uptake. Results have revealed an intimate connection between 18F-FDG uptake and hepatocellular carcinoma differentiation status. This study assessed the diagnostic potential of conventional and three-dimensional metabolic 18F-FDG-positron emission tomography/computed tomography parameters in differentiating Edmondson grade II from grade III hepatocellular carcinoma.
Publish Date 2025-09-24 09:02
Citation <p>Niu XB, Li YP, Chao FF, Mei XL, Han XM, Wang RH. Diagnostic significance of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography in differentiating Edmondson grade II and III hepatocellular carcinoma. <i>World J Gastrointest Surg</i> 2025; 17(9): 107301</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i9/107301.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i9.107301
Full Article (PDF) WJGS-17-107301-with-cover.pdf
Manuscript File 107301_Auto_Edited_080947.docx
Answering Reviewers 107301-answering-reviewers.pdf
Audio Core Tip 107301-audio.m4a
Biostatistics Review Certificate 107301-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 107301-conflict-of-interest-statement.pdf
Copyright License Agreement 107301-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 107301-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 107301-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 107301-non-native-speakers.pdf
Peer-review Report 107301-peer-reviews.pdf
Scientific Misconduct Check 107301-scientific-misconduct-check.png
Scientific Editor Work List 107301-scientific-editor-work-list.pdf
CrossCheck Report 107301-crosscheck-report.pdf