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Articles Published Processes
12/19/2025 8:32:39 AM | Browse: 6 | Download: 19
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Received |
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2025-05-30 05:49 |
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Peer-Review Started |
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2025-05-30 05:50 |
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First Decision by Editorial Office Director |
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2025-06-23 01:54 |
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Return for Revision |
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2025-06-23 01:54 |
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Revised |
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2025-07-03 03:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-09-18 02:54 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-09-18 08:36 |
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Articles in Press |
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2025-09-18 08:36 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-28 09:29 |
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Publish the Manuscript Online |
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2025-12-19 08:32 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Gut microbiota and metabolic-associated steatosis liver disease: Unveiling mechanisms and opportunities for therapeutic intervention
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Resha Dermawansyah Rusman, Fardah Akil, Muhammad Luthfi Parewangi, Nu'man AS Daud, Rini Bachtiar, Susanto Hendra Kusuma and Amelia Rifai |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Resha Dermawansyah Rusman, MD, Division of Gastroenterology-Hepatology, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Jl. Perintis Kemerdekaan Km. 10, Makassar 90245, Sulawesi Selatan, Indonesia. reshadermawan@unhas.ac.id |
| Key Words |
Gut-liver axis; Chronic liver disease; Gut microbiota; Metabolic associated steatotic liver disease; Intervention |
| Core Tip |
Metabolic-associated steatotic liver disease (MASLD) has developed into a worldwide health dilemma closely related to metabolic diseases such as obesity and type 2 diabetes mellitus. Mounting evidence highlights the importance of the gut microbiota in the pathogenesis of MASLD, as gut dysbiosis induced by increased gut permeability, endotoxemia and the action of microbial metabolites have been demonstrated to lead to hepatic steatosis, inflammation and fibrosis. Therapeutic potential of modulating gut microbiota with probiotics, prebiotics, synbiotics and microbiota-derived interventions is an emerging approach. Herein, we cover the gut–liver axis in MASLD drawing on insights from mechanistic pathways to microbiota-based therapeutic strategies that may transform MASLD management. |
| Publish Date |
2025-12-19 08:32 |
| Citation |
Rusman RD, Akil F, Parewangi ML, Daud NA, Bachtiar R, Kusuma SH, Rifai A. Gut microbiota and metabolic-associated steatosis liver disease: Unveiling mechanisms and opportunities for therapeutic intervention. World J Exp Med 2025; 15(4): 107316 |
| URL |
https://www.wjgnet.com/2220-315x/full/v15/i4/107316.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v15.i4.107316 |
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