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Articles Published Processes
7/15/2025 8:26:25 AM | Browse: 48 | Download: 290
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Received |
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2025-03-21 17:07 |
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Peer-Review Started |
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2025-03-25 00:08 |
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First Decision by Editorial Office Director |
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2025-03-27 09:40 |
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Return for Revision |
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2025-03-27 09:40 |
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Revised |
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2025-04-10 01:30 |
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Publication Fee Transferred |
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2025-04-15 06:26 |
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Second Decision by Editor |
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2025-06-03 10:29 |
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Second Decision by Editor-in-Chief |
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2025-06-06 10:37 |
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Final Decision by Editorial Office Director |
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2025-06-10 08:05 |
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Articles in Press |
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2025-06-10 08:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-03 01:07 |
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Publish the Manuscript Online |
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2025-07-15 08:26 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Sodium-glucose co-transporter 2 inhibitors improve insulin resistance and β-cell function in type 2 diabetes: A meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shang-Yu Chai, Ru-Ya Zhang, Zhi-Yuan Ning, Yi-Man Zheng, Rajpathak Swapnil and Li-Nong Ji |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Li-Nong Ji, MD, Professor, Department of Endocrinology, People’s Hospital of Peking University, Xicheng District, Beijing 100044, China. jiln@bjmu.edu.cn |
| Key Words |
β-cell function; Homeostasis model assessment; Insulin resistance; Meta-analysis; Sodium-glucose co-transporter 2 inhibitors |
| Core Tip |
This meta-analysis, based on 24 randomized controlled trials, showed that sodium-glucose cotransporter 2 (SGLT2) inhibitors significantly improve insulin resistance and β-cell function in patients with type 2 diabetes (T2D), as evidenced by reductions in homeostasis model assessment of insulin resistance and increases in β-cell function. These findings highlight the potential of SGLT2 inhibitors to alleviate insulin resistance and improve β-cell function beyond glucose lowering. These results provide novel insights into the therapeutic role of SGLT2 inhibitors in managing T2D and underscore their ability to modify disease progression by targeting key pathophysiological mechanisms. |
| Publish Date |
2025-07-15 08:26 |
| Citation |
Chai SY, Zhang RY, Ning ZY, Zheng YM, Swapnil R, Ji LN. Sodium-glucose co-transporter 2 inhibitors improve insulin resistance and β-cell function in type 2 diabetes: A meta-analysis. World J Diabetes 2025; 16(7): 107335 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i7/107335.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i7.107335 |
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