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7/17/2025 8:43:48 AM | Browse: 6 | Download: 26
Publication Name World Journal of Orthopedics
Manuscript ID 107337
Country Russia
Received
2025-03-28 05:45
Peer-Review Started
2025-03-28 05:45
To Make the First Decision
Return for Revision
2025-04-15 07:09
Revised
2025-04-27 08:41
Second Decision
2025-06-06 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-06-07 03:03
Articles in Press
2025-06-07 03:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-07-08 07:23
Publish the Manuscript Online
2025-07-17 08:43
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Minireviews
Article Title Effectiveness of the induced membrane technique in aseptic and infected long-bone defect management: Are there any differences?
Manuscript Source Invited Manuscript
All Author List Alexander L Shastov, Sergey N Kolchin and Tatiana A Malkova
ORCID
Author(s) ORCID Number
Alexander L Shastov http://orcid.org/0000-0001-7434-1404
Sergey N Kolchin http://orcid.org/0000-0003-1606-4749
Tatiana A Malkova http://orcid.org/0000-0002-4301-9161
Funding Agency and Grant Number
Corresponding Author Tatiana A Malkova, Department of Medical Information and Analysis, Ilizarov National Medical Research Center for Traumatology and Orthopaedics, 6, M. Ulianova street, Kurgan 640014, Russia. tmalkova@mail.ru
Key Words Long bone; Nonunion; Defect; Induced membrane technique; Infection; Spacer; Intramedullary nail; External fixator; Osteomyelitis
Core Tip The induced membrane (IM) technique (IMT) has been mostly used for severe long bone defects due to open fractures and infected nonunion. The clinical studies available show its performance and outcomes on relatively small samples of patients and they are mostly infected cases. The surgeon should adequately resect non-vital tissues to prevent bone auto- or allograft lysis due to possible reinfection. The IMT gives a chance for the infection to heal after thorough debridement within the waiting period during stage 1. Its implementation frequently needs soft-tissue procedures and several grafting materials to add into the IM in critical size defects. Internal fixation is a preferred method of bone fixation to avoid the risks of external fixation complications. The interval between the stages and duration of antibiotics administration are longer in infected cases.
Publish Date 2025-07-17 08:43
Citation <p>Shastov AL, Kolchin SN, Malkova TA. Effectiveness of the induced membrane technique in aseptic and infected long-bone defect management: Are there any differences? <i>World J Orthop</i> 2025; 16(7): 107337</p>
URL https://www.wjgnet.com/2218-5836/full/v16/i7/107337.htm
DOI https://dx.doi.org/10.5312/wjo.v16.i7.107337
Full Article (PDF) WJO-16-107337-with-cover.pdf
Manuscript File 107337_Auto_Edited_061926.docx
Answering Reviewers 107337-answering-reviewers.pdf
Audio Core Tip 107337-audio.m4a
Conflict-of-Interest Disclosure Form 107337-conflict-of-interest-statement.pdf
Copyright License Agreement 107337-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 107337-non-native-speakers.pdf
Peer-review Report 107337-peer-reviews.pdf
Scientific Misconduct Check 107337-scientific-misconduct-check.png
Scientific Editor Work List 107337-scientific-editor-work-list.pdf
CrossCheck Report 107337-crosscheck-report.pdf