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Articles Published Processes
7/14/2025 12:56:02 PM | Browse: 20 | Download: 83
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Received |
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2025-03-23 16:54 |
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Peer-Review Started |
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2025-03-23 16:55 |
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To Make the First Decision |
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Return for Revision |
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2025-04-09 11:08 |
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Revised |
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2025-04-22 10:25 |
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Second Decision |
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2025-06-12 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-12 09:06 |
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Articles in Press |
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2025-06-12 09:06 |
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Publication Fee Transferred |
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2025-04-23 00:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-07-02 04:07 |
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Publish the Manuscript Online |
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2025-07-14 12:56 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Predictive value of neutrophil-to-lymphocyte ratio combined with carcinoembryonic antigen in postoperative adjuvant chemotherapy after gastric cancer surgery
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuan-Zheng Zhao, Jia-Qi Han, Xin-Ran Zhao, Zi-Yuan Wang, Kai-Yu He, Yong-Sheng Duan and Hong-Xia Lu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hong-Xia Lu, Chief Physician, Full Professor, Head, Department of Gastroenterology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, No. 3 Zhigong New Street, Xinghualing District, Taiyuan 030013, Shanxi Province, China. luhongxia@sxmu.edu.cn |
| Key Words |
Neutrophil-to-lymphocyte ratio; Carcinoembryonic antigen; Gastric cancer; Adjuvant chemotherapy; Tumor microenvironment |
| Core Tip |
This investigation conducted a retrospective analysis on a cohort of gastric cancer patients, revealing a 32% disparity in therapeutic efficacy of postoperative adjuvant chemotherapy across distinct neutrophil-to-lymphocyte ratio (NLR)- carcinoembryonic antigen (CEA) stratification groups. Utilizing a stratified approach based on adjuvant chemotherapy administration status, we performed covariate-adjusted Cox proportional hazards regression analyses to evaluate comparative therapeutic outcomes among NLR-based, CEA-based, and combined NLR-CEA stratification models. The findings demonstrate significantly greater differential therapeutic benefits in the combined NLR-CEA stratification group compared to isolated NLR or CEA parameter stratification, suggesting synergistic prognostic value of this composite biomarker approach. |
| Publish Date |
2025-07-14 12:56 |
| Citation |
<p>Zhao YZ, Han JQ, Zhao XR, Wang ZY, He KY, Duan YS, Lu HX. Predictive value of neutrophil-to-lymphocyte ratio combined with carcinoembryonic antigen in postoperative adjuvant chemotherapy after gastric cancer surgery. <i>World J Gastrointest Oncol</i> 2025; 17(7): 107399</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i7/107399.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i7.107399 |
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