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Articles Published Processes
8/8/2025 10:23:11 AM | Browse: 158 | Download: 352
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Received |
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2025-03-24 04:39 |
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Peer-Review Started |
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2025-03-25 02:33 |
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First Decision by Editorial Office Director |
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2025-04-07 12:29 |
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Return for Revision |
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2025-04-07 12:29 |
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Revised |
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2025-04-19 02:01 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-06-20 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-06-20 09:26 |
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Articles in Press |
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2025-06-20 09:26 |
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Edit the Manuscript by Language Editor |
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2025-06-23 19:12 |
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Typeset the Manuscript |
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2025-07-22 02:37 |
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Publish the Manuscript Online |
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2025-08-08 10:23 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Review |
| Article Title |
Cell-free DNA in extracellular vesicles: A candidate biomarker of schizophrenia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yu-Long Bai, Shi-Fa Ma, Dong-Dong Qi, Chuang Guo, Peng Liu and Kuan-Jun He |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Inner Mongolia Autonomous Region |
2024LHMS08003 |
| Science and Technology Program of the Joint Fund of Scientific Research for the Public Hospitals of Inner Mongolia Academy of Medical Sciences |
2024GLLH0844 |
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| Corresponding Author |
Kuan-Jun He, PhD, Professor, College of Life Sciences and Food Engineering, Inner Mongolia Minzu University, No. 996 Xilamulun Street, Tongliao 028000, Inner Mongolia Autonomous Region, China. hekuanjun@imun.edu.cn |
| Key Words |
Schizophrenia; Cell-free DNA; Extracellular vesicles; Mitochondrial damage; Inflammation |
| Core Tip |
Schizophrenia (SCZ) is a severe mental disorder characterized by multi-dimensional dysfunction in perception, cognition, emotion, and behavior. Recent research has highlighted the critical role of cell-free DNA (cf-DNA) carried by extracellular vesicles in SCZ. Abnormal expression of cf-DNA may be potentially linked to the pathological progression of SCZ. This review provides the molecular regulatory mechanisms of extracellular vesicle-derived cf-DNA in the pathogenesis and progression of SCZ, emphasizing its potential as a novel diagnostic marker and its promising clinical applications, thereby offering a new avenue for exploring the biological underpinnings of the disease and developing objective diagnostic tools. |
| Publish Date |
2025-08-08 10:23 |
| Citation |
Bai YL, Ma SF, Qi DD, Guo C, Liu P, He KJ. Cell-free DNA in extracellular vesicles: A candidate biomarker of schizophrenia. World J Psychiatry 2025; 15(8): 107404 |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i8/107404.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i8.107404 |
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