| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
Serum factor V and arterial lactate levels predict graft survival in liver transplant recipients with aminotransferase above five thousand
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Gabriel Lazzarotto-da-Silva, Bruno Marches Chaves, Flávia Heinz Feier, Pablo Duarte Rodrigues, Tomaz Jesus Maria Grezzana-Filho, Alexandre de Araujo, Mario Reis Alvares-da-Silva, Roberta Cabral Marchiori, Marcio Fernandes Chedid and Cleber Rosito Pinto Kruel |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Financiamento e Incentivo à Pesquisa of Hospital de Clínicas de Porto Alegre |
No. 170271 |
|
| Corresponding Author |
Marcio Fernandes Chedid, MD, PhD, Professor, Liver Transplant and Hepatobiliary Surgery Unit, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre 90035-007, Rio Grande do Sul, Brazil. mchedid@hcpa.edu.br |
| Key Words |
Aminotransferase; Liver transplantation; Early allograft failure; Factor V; Lactate |
| Core Tip |
Among 341 liver transplant recipients, 25 had an aminotransferase level > 5000 U/L. Early allograft failure (death or re-transplantation within 90 days) occurred in 11 patients. One-year and five-year graft survival rates were 51.7% and 42.6%, respectively. However, approximately 50% of these patients withstood initial graft injury and had a satisfactory long-term prognosis. Therefore, early identification of patients who will recover graft function or undergo graft loss is paramount. Serum factor V and arterial lactate levels can aid in deciding whether to relist patients to retransplantation early in the postoperative period. |
| Publish Date |
2025-11-19 05:57 |
| Citation |
Lazzarotto-da-Silva G, Chaves BM, Feier FH, Rodrigues PD, Grezzana-Filho TJM, de Araujo A, Alvares-da-Silva MR, Marchiori RC, Chedid MF, Kruel CRP. Serum factor V and arterial lactate levels predict graft survival in liver transplant recipients with aminotransferase above five thousand. World J Transplant 2025; 15(4): 107461 |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i4/107461.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i4.107461 |
