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8/4/2025 12:11:42 PM | Browse: 44 | Download: 225
Publication Name World Journal of Methodology
Manuscript ID 107468
Country United States
Received
2025-03-25 07:14
Peer-Review Started
2025-04-02 09:00
First Decision by Editorial Office Director
2025-04-18 01:29
Return for Revision
2025-04-18 01:29
Revised
2025-04-28 15:07
Publication Fee Transferred
Second Decision by Editor
2025-06-18 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-06-18 08:03
Articles in Press
2025-06-18 08:03
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-07-07 10:25
Publish the Manuscript Online
2025-08-04 12:11
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Meta-Analysis
Article Title Association of neutrophil-lymphocyte ratio with cardiovascular and all-cause mortality in patients receiving chronic hemodialysis: Systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Roopeessh Vempati, Nanush Damarlapally, Srivatsa Surya Vasudevan, Viral Patel, Prathibha Banda, Denise Mourad, Harshavardhan Polamarasetty, Gaurav Mathur, Afrasayab Khan, Rupak Desai, Iqbal Ratnani and Salim Surani
ORCID
Author(s) ORCID Number
Roopeessh Vempati http://orcid.org/0000-0001-5966-909X
Nanush Damarlapally http://orcid.org/0000-0002-0688-659X
Srivatsa Surya Vasudevan http://orcid.org/0000-0002-6998-1658
Viral Patel http://orcid.org/0000-0002-6245-0299
Prathibha Banda http://orcid.org/0009-0006-2935-8454
Denise Mourad http://orcid.org/0009-0003-8599-6619
Harshavardhan Polamarasetty http://orcid.org/0009-0008-4162-4019
Gaurav Mathur http://orcid.org/0009-0003-3196-8356
Afrasayab Khan http://orcid.org/0009-0005-3862-418X
Rupak Desai http://orcid.org/0000-0002-5315-6426
Iqbal Ratnani http://orcid.org/0000-0002-1168-3041
Salim Surani http://orcid.org/0000-0001-7105-4266
Funding Agency and Grant Number
Corresponding Author Salim Surani, MD, Professor, Department of Medicine & Pharmacology, Texas A&M University, 40 Bizzell Street, College Station, TX 77843, United States. srsurani@hotmail.com
Key Words Neutrophil-lymphocyte ratio; Chronic hemodialysis; Cardiovascular mortality; All-cause mortality; Inflammation; Inflammatory markers; Dialysis outcomes; Hematological biomarkers; Dialysis-associated cardiovascular disease
Core Tip This systematic review and meta-analysis evaluate the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) in patients undergoing chronic hemodialysis (HD). Elevated NLR was significantly associated with increased all-cause and cardiovascular mortality in this population. By pooling adjusted hazard ratios and assessing heterogeneity and diagnostic performance via the area under the curve, the study highlights NLR as a potentially valuable and accessible biomarker for risk stratification in HD patients. Findings support its clinical use, while emphasizing the need for standardized cutoffs and prospective validation.
Publish Date 2025-08-04 12:11
Citation

Vempati R, Damarlapally N, Vasudevan SS, Patel V, Banda P, Mourad D, Polamarasetty H, Mathur G, Khan A, Desai R, Ratnani I, Surani S. Association of neutrophil-lymphocyte ratio with cardiovascular and all-cause mortality in patients receiving chronic hemodialysis: Systematic review and meta-analysis. World J Methodol 2025; 15(4): 107468

URL https://www.wjgnet.com/2222-0682/full/v15/i4/107468.htm
DOI https://dx.doi.org/10.5662/wjm.v15.i4.107468
Full Article (PDF) WJM-15-107468-with-cover.pdf
PRISMA 2009 Checklist 107468-PRISMA-2009-Checklist.pdf
Manuscript File 107468_Auto_Edited_071257.docx
Answering Reviewers 107468-answering-reviewers.pdf
Audio Core Tip 107468-audio.m4a
Biostatistics Review Certificate 107468-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 107468-conflict-of-interest-statement.pdf
Copyright License Agreement 107468-copyright-assignment.pdf
Supplementary Material 107468-supplementary-material.pdf
Peer-review Report 107468-peer-reviews.pdf
Scientific Misconduct Check 107468-scientific-misconduct-check.png
Scientific Editor Work List 107468-scientific-editor-work-list.pdf
CrossCheck Report 107468-crosscheck-report.pdf