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Articles Published Processes
8/21/2025 5:29:10 AM | Browse: 42 | Download: 52
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Received |
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2025-03-25 05:58 |
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Peer-Review Started |
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2025-03-25 05:59 |
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To Make the First Decision |
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Return for Revision |
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2025-04-01 12:42 |
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Revised |
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2025-04-12 21:36 |
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Second Decision |
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2025-07-09 09:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-10 07:23 |
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Articles in Press |
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2025-07-10 07:23 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-07-15 00:53 |
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Typeset the Manuscript |
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2025-08-13 02:28 |
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Publish the Manuscript Online |
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2025-08-21 05:29 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Review |
| Article Title |
Current perspectives on regenerative potential of mesenchymal stem cells in alleviating cardiac injuries: Molecular pathways and therapeutic enhancement
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Asmaa M ShamsEldeen, Sara A Hosny, Khaled Maghib and Hend Ashour |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Asmaa M ShamsEldeen, Assistant Professor, MD, Department of Physiology, Cairo University, Al-Saray Street, Cairo 11956, Egypt. asmaa82shamseldeen@gmail.com |
| Key Words |
Stem cells; Homing; Paracrine effects; Extracellular vesicles; Cardiac damage |
| Core Tip |
In clinical and experimental research, mesenchymal stem cells (MSCs) are currently thought to exert a promising therapeutic potential. Globally, cardiovascular diseases remain the leading cause of mortality. Thus, studying the specific molecular pathways by which MSCs mitigate cardiac injuries is essential in improving their therapeutic applications in the future. Through their immunoregulatory, anti-apoptotic, antifibrotic, antioxidant, and angiogenic activities, MSCs can influence the course of cardiovascular diseases. Successful homing and engraftment are necessary for MSCs’ regenerative capacity. Meanwhile, this review also focused on the underlying mechanisms of MSCs homing and the challenges that may hinder their effects. |
| Publish Date |
2025-08-21 05:29 |
| Citation |
<p>ShamsEldeen AM, Hosny SA, Maghib K, Ashour H. Current perspectives on regenerative potential of mesenchymal stem cells in alleviating cardiac injuries: Molecular pathways and therapeutic enhancement. <i>World J Stem Cells</i> 2025; 17(8): 107480</p> |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i8/107480.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i8.107480 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
