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Articles Published Processes
7/22/2025 9:23:06 AM | Browse: 4 | Download: 27
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Received |
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2025-03-25 06:35 |
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Peer-Review Started |
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2025-03-25 06:35 |
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To Make the First Decision |
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Return for Revision |
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2025-04-16 10:41 |
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Revised |
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2025-04-18 07:15 |
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Second Decision |
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2025-06-05 02:42 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-05 08:35 |
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Articles in Press |
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2025-06-05 08:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-06-08 22:20 |
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Typeset the Manuscript |
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2025-07-11 08:40 |
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Publish the Manuscript Online |
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2025-07-22 09:23 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Proton pump inhibitors and mortality in cancer patients: Unraveling the complex link
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ibtehaj Tariq, Qurat Ul Ain Iftikhar and Abdulqadir J Nashwan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Abdulqadir J Nashwan, PhD, Department of Nursing, Hamad Medical Corporation, P.O. Box 3050, Doha 3050, Qatar. anashwan@hamad.qa |
| Key Words |
Proton pump inhibitors; Cancer mortality; Confounding by indication; Reverse causality; Polypharmacy; Gastrointestinal complications; Acid suppression therapy; Clinical pharmacology; Oncology treatment; Observational study |
| Core Tip |
The original study by Krishnan et al proposes a link between proton pump inhibitors use and increased all-cause mortality. Our critique highlights methodological limitations, including residual confounding, indication bias, and a lack of causality assessment. We draw attention to the need for cautious interpretation and advocate for well-designed prospective studies before drawing definitive clinical conclusions. |
| Publish Date |
2025-07-22 09:23 |
| Citation |
<p>Tariq I, Iftikhar QUA, Nashwan AJ. Proton pump inhibitors and mortality in cancer patients: Unraveling the complex link. <i>World J Clin Oncol</i> 2025; 16(7): 107509</p> |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i7/107509.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i7.107509 |
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