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Articles Published Processes
7/15/2025 8:26:28 AM | Browse: 2 | Download: 6
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Received |
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2025-03-25 06:47 |
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Peer-Review Started |
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2025-03-26 02:24 |
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To Make the First Decision |
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Return for Revision |
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2025-04-17 04:03 |
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Revised |
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2025-04-24 01:41 |
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Second Decision |
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2025-06-04 10:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-06-11 08:16 |
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Articles in Press |
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2025-06-11 08:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-06-15 22:57 |
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Typeset the Manuscript |
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2025-06-27 01:19 |
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Publish the Manuscript Online |
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2025-07-15 08:26 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Minireviews |
Article Title |
Metformin-induced vitamin B12 deficiency: An underdiagnosed cause of diabetic neuropathy
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Manuscript Source |
Invited Manuscript |
All Author List |
Mauricio Alvarez, Andres E Prieto, Natalia Portilla, Diana Moya, Oswaldo Rincon and Isaac Guzman |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Mauricio Alvarez, Department of Endocrinology, Hospital Militar Central, Carrera 7a n 94 a 47, Bogotá 110221, Colombia. mauricioalvarez613@gmail.com |
Key Words |
Metformin; Vitamin B12 deficiency; Diabetic neuropathy; Type 2 diabetes mellitus; Clinical guidelines |
Core Tip |
Metformin-induced vitamin B12 deficiency is common in type 2 diabetes and is increasingly linked to diabetic neuropathy. Despite emerging evidence supporting screening and supplementation, major clinical guidelines provide inconsistent recommendations. Given B12’s safety, affordability, and potential benefits, systematic screening should be prioritized in diabetic patients at risk of deficiency, especially those with neuropathy. |
Publish Date |
2025-07-15 08:26 |
Citation |
<p>Alvarez M, Prieto AE, Portilla N, Moya D, Rincon O, Guzman I. Metformin-induced vitamin B12 deficiency: An underdiagnosed cause of diabetic neuropathy. <i>World J Diabetes</i> 2025; 16(7): 107514</p> |
URL |
https://www.wjgnet.com/1948-9358/full/v16/i7/107514.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v16.i7.107514 |
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